Bernabeu Mora Roberto, Sánchez Nieto Juan Miguel, Nieto Olivares Andrés
Pneumology Service, Hospital General Universitario Morales Meseguer, C/Marques de los Vélez, s/n, 30008, Murcia, Spain.
Pathological Anatomy Service, Hospital General Universitario Morales Meseguer, Murcia, Spain.
Int J Hematol. 2009 Sep;90(2):153-156. doi: 10.1007/s12185-009-0372-8. Epub 2009 Jul 17.
Primary pulmonary lymphoma (PPL) is an uncommon pathology and is usually of the B-cell type, originating in lymphoid tissue associated with the bronchial mucosa (MALT/BALT lymphoma). Very few cases of T-cell PPL, the majority diagnosed by open lung biopsy, have been described in medical literature. We report a case of an immunocompetent patient with fever and bilateral pulmonary nodules, diagnosed with T-cell PPL by transbronchial biopsy. The patient's condition deteriorated and she responded poorly to chemotherapy. PPL should be included in the differential diagnosis of patients with fever and bilateral pulmonary nodules.
原发性肺淋巴瘤(PPL)是一种罕见的病理类型,通常为B细胞型,起源于与支气管黏膜相关的淋巴组织(黏膜相关淋巴组织/支气管相关淋巴组织淋巴瘤)。医学文献中描述的T细胞PPL病例极少,大多数通过开胸肺活检确诊。我们报告一例免疫功能正常的患者,有发热和双侧肺结节,经支气管活检诊断为T细胞PPL。患者病情恶化,对化疗反应不佳。PPL应纳入发热和双侧肺结节患者的鉴别诊断。