C型病毒gag基因在鸡胚成纤维细胞和禽肉瘤病毒转化的哺乳动物细胞中的表达。
Type C viral gag gene expression in chicken embryo fibroblasts and avian sarcoma virus-transformed mammalian cells.
作者信息
Reynolds F H, Hanson C A, Aaronson S A, Stephenson J R
出版信息
J Virol. 1977 Jul;23(1):74-9. doi: 10.1128/JVI.23.1.74-79.1977.
Abstract
Sensitive radioimmunoassays were developed for avian type C viral gag gene-coded proteins. These assays were used to examine the restriction to virus production by avian embryo cells and mammalian cells transformed by avian sarcoma viruses. The results indicate that although a high-molecular-weight primary translational product of the gag gene is expressed, its cleavage and processing are incomplete. Furthermore, analysis of intermediate cleavage products provided information regarding the order of sequences coding for the individual viral proteins within the avian type C viral gag gene.
摘要
已开发出用于检测禽C型病毒gag基因编码蛋白的灵敏放射免疫测定法。这些测定法用于检测禽胚胎细胞和被禽肉瘤病毒转化的哺乳动物细胞对病毒产生的限制作用。结果表明，尽管gag基因的高分子量初级翻译产物能够表达，但其切割和加工并不完整。此外，对中间切割产物的分析提供了有关禽C型病毒gag基因内各个病毒蛋白编码序列顺序的信息。
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本文引用的文献
1
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J Virol. 1974 Feb;13(2):340-6. doi: 10.1128/JVI.13.2.340-346.1974.
2
Protein measurement with the Folin phenol reagent.使用福林酚试剂进行蛋白质测定。
J Biol Chem. 1951 Nov;193(1):265-75.
3
THE PREPARATION OF I-131-LABELLED HUMAN GROWTH HORMONE OF HIGH SPECIFIC RADIOACTIVITY.高比放射性碘-131标记人生长激素的制备
Biochem J. 1963 Oct;89(1):114-23. doi: 10.1042/bj0890114.
4
Presence of chicken tumour virus in the sarcoma of the adult rat inoculated after birth with Rous sarcoma tissue.出生后接种劳斯肉瘤组织的成年大鼠肉瘤中鸡肿瘤病毒的存在情况。
Nature. 1960 Jun 18;186:980-1. doi: 10.1038/186980b0.
5
Cleavage of structural proteins during the assembly of the head of bacteriophage T4.在噬菌体T4头部组装过程中结构蛋白的切割
Nature. 1970 Aug 15;227(5259):680-5. doi: 10.1038/227680a0.
6
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J Virol. 1974 Dec;14(6):1419-29. doi: 10.1128/JVI.14.6.1419-1429.1974.
7
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Proc Natl Acad Sci U S A. 1973 Jun;70(6):1734-8. doi: 10.1073/pnas.70.6.1734.
9
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J Virol. 1971 Nov;8(5):778-85. doi: 10.1128/JVI.8.5.778-785.1971.
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