内源性白血病病毒厌氧诱导的明显转录后阻断
Apparent posttranscriptional block to anaerobic induction of endogenous leukemia virus.
作者信息
Whitaker-Dowling P A, Marotti K R, Anderson G R
出版信息
J Virol. 1979 Oct;32(1):234-9. doi: 10.1128/JVI.32.1.234-239.1979.
Abstract
Uninfected Fischer rat cells were induced by anaerobic stress to transcribe high levels of endogenous type C leukemia virus RNA. Complete 35S virus RNA with attached polyadenylic acid sequences was found associated with polysomes, indicating functional mRNA. Since no mature virus was released under these conditions, the presence of a posttranscriptional block to complete virus synthesis is strongly indicated.
摘要
未感染的费希尔大鼠细胞在无氧应激诱导下转录出高水平的内源性C型白血病病毒RNA。发现带有多聚腺苷酸序列的完整35S病毒RNA与多核糖体相关联，表明其为功能性信使核糖核酸。由于在这些条件下没有释放出成熟病毒，强烈提示在病毒合成过程中存在转录后阻断。
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本文引用的文献
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