内源性白血病病毒厌氧诱导的明显转录后阻断
Apparent posttranscriptional block to anaerobic induction of endogenous leukemia virus.
作者信息
Whitaker-Dowling P A, Marotti K R, Anderson G R
出版信息
J Virol. 1979 Oct;32(1):234-9. doi: 10.1128/JVI.32.1.234-239.1979.
Abstract
Uninfected Fischer rat cells were induced by anaerobic stress to transcribe high levels of endogenous type C leukemia virus RNA. Complete 35S virus RNA with attached polyadenylic acid sequences was found associated with polysomes, indicating functional mRNA. Since no mature virus was released under these conditions, the presence of a posttranscriptional block to complete virus synthesis is strongly indicated.
摘要
未感染的费希尔大鼠细胞在无氧应激诱导下转录出高水平的内源性C型白血病病毒RNA。发现带有多聚腺苷酸序列的完整35S病毒RNA与多核糖体相关联，表明其为功能性信使核糖核酸。由于在这些条件下没有释放出成熟病毒，强烈提示在病毒合成过程中存在转录后阻断。
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本文引用的文献
1
The effects of inhibitors of RNA and DNA synthesis on protein synthesis and polysome levels in mouse L-cells.RNA和DNA合成抑制剂对小鼠L细胞中蛋白质合成及多核糖体水平的影响。
J Cell Physiol. 1973 Oct;82(2):133-50. doi: 10.1002/jcp.1040820202.
2
Induction of type-C RNA virus by cycloheximide: increased expression of virus-specific RNA.放线菌酮诱导C型RNA病毒：病毒特异性RNA表达增加。
Proc Natl Acad Sci U S A. 1974 Oct;71(10):3941-5. doi: 10.1073/pnas.71.10.3941.
3
Murine leukemia virus: high-frequency activation in vitro by 5-iododeoxyuridine and 5-bromodeoxyuridine.鼠白血病病毒：5-碘脱氧尿苷和5-溴脱氧尿苷在体外的高频激活作用
Science. 1971 Oct 8;174(4005):155-6. doi: 10.1126/science.174.4005.155.
4
Genetic factors influencing C-type RNA virus induction.影响C型RNA病毒诱导的遗传因素。
J Exp Med. 1972 Jul 1;136(1):175-84. doi: 10.1084/jem.136.1.175.
5
Retroviruses.逆转录病毒
Annu Rev Biochem. 1978;47:35-88. doi: 10.1146/annurev.bi.47.070178.000343.
6
Intracellular precursors to the major glycoprotein of avian oncoviruses in chicken embryo fibroblasts.鸡胚成纤维细胞中禽肿瘤病毒主要糖蛋白的细胞内前体。
J Virol. 1978 Mar;25(3):845-51. doi: 10.1128/JVI.25.3.845-851.1978.
7
Expression of murine sarcoma virus genes in uninfected rat cells subjected to anaerobic sress.鼠肉瘤病毒基因在遭受无氧应激的未感染大鼠细胞中的表达。
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Virology. 1977 Jun 1;79(1):1-13. doi: 10.1016/0042-6822(77)90329-4.
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