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中年男性工人工作压力与桡动脉波反射的关系。

Relationship between job strain and radial arterial wave reflection in middle-aged male workers.

机构信息

Department of Hygiene and Public Health, Nippon Medical School, 1-1-5 Sendagi, Bunkyo-ku, Tokyo 113-8602, Japan.

出版信息

Prev Med. 2009 Aug-Sep;49(2-3):260-4. doi: 10.1016/j.ypmed.2009.07.005. Epub 2009 Jul 17.

Abstract

OBJECTIVE

This study examined the relationship between job stain and radial arterial wave reflection as expressed by the augmentation index (AI), a marker of cardiovascular risk, in middle-aged male workers.

METHODS

Radial AI was measured using automated applanation tonometry in 808 working men (mean age; 47+/-5 years) at a company in Kanagawa, Japan in 2007. An elevated AI represents the deterioration of arterial properties and increased cardiovascular risk. Job demand and job control (decision latitude) were evaluated by a self-administered, Brief Job Stress Questionnaire. High job strain was defined as the combination of high job demand and low job control.

RESULTS

In the entire study population, the mean+/-SD and the median of AI were 74+/-13% and 75%, respectively. High job strain was seen in 267 subjects. In a multiple logistic regression analysis with adjustment for multiple potential confounders, high job strain showed a significantly increased odds ratio (1.47, 95% CI; 1.04-2.09, P=0.029) for an elevated AI (> or =75%).

CONCLUSION

High job strain was significantly associated with an elevated radial AI. The measurement of AI may be useful when incorporated in workplace interventions to reduce the risk of cardiovascular disease, especially at sites where workers tend to perceive high job strain.

摘要

目的

本研究旨在探讨工作压力与心血管风险标志物——脉搏波反射增强指数(AI)之间的关系,研究对象为日本神奈川县某公司的 808 名中年男性工人。

方法

2007 年,使用自动平面张力测定法测量了 808 名男性工人(平均年龄为 47+/-5 岁)的桡动脉 AI。AI 升高表示动脉功能恶化和心血管风险增加。通过自我管理的简短工作压力问卷评估工作需求和工作控制(决策自由度)。高工作压力定义为高工作需求和低工作控制的组合。

结果

在整个研究人群中,AI 的平均值为 74+/-13%,中位数为 75%。267 名参与者表现出高工作压力。在调整了多种潜在混杂因素的多变量逻辑回归分析中,高工作压力与 AI 升高(>或=75%)的比值比显著增加(1.47,95%CI;1.04-2.09,P=0.029)。

结论

高工作压力与桡动脉 AI 升高显著相关。在工作场所干预措施中,当需要降低心血管疾病风险时,AI 的测量可能会很有用,特别是在工人感知工作压力较高的地方。

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