Kang Myung Gun, Koh Sang Baek, Cha Bong Suk, Park Jong Ku, Baik Soon Koo, Chang Sei Jin
Department of Preventive Medicine, College of Medicine, Chosun University, Gwangju, South Korea.
Prev Med. 2005 May;40(5):583-8. doi: 10.1016/j.ypmed.2004.07.018.
This study examined whether job stress (work demand and decision latitude) is associated with smoking, blood pressure, lipid level (total cholesterol, triglyceride, HDL cholesterol), and homocystein as risk factors for cardiovascular disease in Korean male workers.
Study subjects of this study were recruited from a sample of 1,071 workers in 20 companies of W city and H counties, and they were grouped into four categories (high strain group, active group, passive group, and low strain group) based on the postulation of Karasek's Job Strain Model. Of them, we invited 160 male workers (40 people each subgroup) using a stratified sampling, and finally, 152 eligible participants were analyzed.
In multivariate analyses, we found that decision latitude was associated with cholesterol, triglyceride, and homocystein and that work demand was related to smoking and systolic blood pressure. Job strain (the combination of high work demand with low decision latitude) was significantly related to higher levels of homocystein after controlling for age, BMI, smoking, and social support at workplace.
These results indicate that job stress is associated with cardiovascular risk factors and might contribute to the development of cardiovascular disease. Some considerations for the future research were discussed.
本研究探讨了工作压力（工作要求和决策自由度）是否与韩国男性工人吸烟、血压、血脂水平（总胆固醇、甘油三酯、高密度脂蛋白胆固醇）以及同型半胱氨酸等心血管疾病风险因素相关。
本研究的受试者从W市和H县20家公司的1071名工人样本中招募，并根据Karasek工作压力模型的假设分为四类（高压力组、积极组、消极组和低压力组）。其中，我们采用分层抽样邀请了160名男性工人（每个亚组40人），最终对152名符合条件的参与者进行了分析。
在多变量分析中，我们发现决策自由度与胆固醇、甘油三酯和同型半胱氨酸相关，工作要求与吸烟和收缩压相关。在控制年龄、体重指数、吸烟和工作场所社会支持后，工作压力（高工作要求与低决策自由度的组合）与较高水平的同型半胱氨酸显著相关。
这些结果表明，工作压力与心血管危险因素相关，可能有助于心血管疾病的发展。讨论了未来研究的一些考虑因素。
