Emadi Seyed Naser, Hosseini-Khalili Alireza, Soroush Mohammadreza, Ardakani Mohammadreza Khodaei, Ghassemi-Broumand Mohammad, Davoodi Seyed Masoud, Amirani Omolbanin, Haines David
Janbazan Medical and Engineering Research Center, Tehran, Iran.
Int J Dermatol. 2009 Sep;48(9):960-3. doi: 10.1111/j.1365-4632.2009.04128.x. Epub 2009 Jul 13.
Sulfur mustard (SM), a chemical weapon used widely during World War I and against Iranians during the Iran-Iraq War of the 1980s, causes massive inflammatory tissue damage in the immediate post-exposure period, resulting in debilitating chronic disease in years to decades following contact with the agent. These syndromes most often are pathologies of the lungs, eyes, and skin, the primary target organs of SM. Typically, they are characterized by severe and increasingly painful inflammation, often accompanied by fibrosis and constriction of the anatomic channels needed for normal life, such as the small airways of the lungs and, in the present report, the urethra.
The present case study is a 43-year-old man with a history of heavy SM exposure to the groin in 1984.
Within 1 year after exposure, the patient was found to have developed meatal stricture, occlusion of the external urethral meatus, and difficulty in urination. Two years post-exposure, he underwent ventral meatotomy and meatoplasty.
This case presents a unique example of the latent effects of SM exposure to the groin, and will be of value in the prevention of similar injury and complications to persons at risk of SM exposure in the future.
芥子气（SM）是一种在第一次世界大战期间被广泛使用的化学武器，在20世纪80年代的两伊战争中被用于对付伊朗人。它在接触后的即刻会导致大量炎症性组织损伤，在接触该毒剂数年至数十年后会引发使人衰弱的慢性病。这些综合征最常见的是肺部、眼睛和皮肤的病变，而这些是芥子气的主要靶器官。通常，它们的特征是严重且日益疼痛的炎症，常伴有纤维化以及对正常生活所需解剖通道的狭窄，如肺部的小气道，在本报告中则是尿道。
本病例研究的是一名43岁男性，他在1984年有腹股沟大量接触芥子气的病史。
接触后1年内，发现该患者出现尿道口狭窄、尿道外口闭塞及排尿困难。接触后2年，他接受了腹侧尿道口切开术和尿道口成形术。
本病例展示了腹股沟接触芥子气潜在影响的一个独特例子，对未来预防有接触芥子气风险人群的类似损伤及并发症具有价值。
