Nie Chunxiao, Song Yuelin, Chen Dong, Xue Peifeng, Tu Pengfei, Wang Keyuan, Chen Jinming
School of Pharmaceutical Sciences, Inner-mongolia medical college, Hohehot 010059, China.
Zhongguo Zhong Yao Za Zhi. 2009 Apr;34(7):858-60.
To investigate the chemical constituents of the leaves of Aquilaria sinensis, and provide a certain of basis for the comprehensive uses of the plant of A. sinensis.
The chemical constituents were isolated by various column chromatographic method. The structures were identified by spectral analyses of NMR, MS, et al.
Thirteen compounds were isolated and identified as 7-hyroxy-5, 4'-dimethoxy flovone (1), 5-hydroxy-7, 4'-dimethoxy flavone (2), luteolin-7-3',4'-trimethyl (3), isocorydine (4), 4-hydroxybenzoic acid (5), triacontenoic (6), hentriacontane (7), alpha-stigmasterol (8), epifriedelanol (9), friedelan (10), friedelin (11), genkwanin (12), 5, 4'-dihyroxy-7, 3'-dimethoxy flovone (13).
Compound 4 was obtained from this genus for the first time, compounds 1, 6-11, 13 were obtained from this species for the first time.
研究白木香叶的化学成分,为白木香植物的综合利用提供一定依据。
采用多种柱色谱法分离化学成分,通过核磁共振(NMR)、质谱(MS)等光谱分析鉴定结构。
分离鉴定出13个化合物,分别为7-羟基-5,4'-二甲氧基黄酮(1)、5-羟基-7,4'-二甲氧基黄酮(2)、木犀草素-7-3',4'-三甲基醚(3)、异紫堇定(4)、4-羟基苯甲酸(5)、三十碳烯酸(6)、三十一烷(7)、α-豆甾醇(8)、表木栓醇(9)、木栓烷(10)、木栓酮(11)、芫花素(12)、5,4'-二羟基-7,3'-二甲氧基黄酮(13)。
化合物4为首次从该属植物中分得,化合物1、6-11、13为首次从该种植物中分得。