Liu Pu, Deng Ruixue, Duan Hongquan, Yin Weiping
Chemical Engineering & Pharmaceutical College, Henan University of Science and Technology, Luoyang 471003, China.
Zhongguo Zhong Yao Za Zhi. 2009 Apr;34(7):867-70.
To study the chemical constituents of Phlomis umbrosa.
Chemical constituents were isolated by repeated column chromatography (Toyopearl HW-40C and preparative HPLC). The structures were elucidated on the basis of spectral data analysis.
Thirteen compounds were identified as oleanolic acid (1), corosolic acid (2), hederagenin (3), arjunolic acid (4), belleric acid (5), 3beta-hydroxy-29-al-12-en-28-oleanoic acid (6), butyrospermol (7), beta-sitosterol (8), daucosterol (9), caffeic acid (10), vanillic acid (11), p-hydroxy-benzoic acid (12), 3, 4-dihydroxy-benzoic acid (13).
Compounds 3 9, 11-13 were isolated from the plant for the first time.
研究糙苏的化学成分。
通过反复柱色谱法（Toyopearl HW - 40C和制备型高效液相色谱）分离化学成分。基于光谱数据分析阐明结构。
鉴定出13种化合物，分别为齐墩果酸（1）、科罗索酸（2）、常春藤皂苷元（3）、阿尔朱诺酸（4）、贝利酸（5）、3β - 羟基 - 29 - 醛基 - 12 - 烯 - 28 - 齐墩果烷酸（6）、牛油果醇（7）、β - 谷甾醇（8）、胡萝卜苷（9）、咖啡酸（10）、香草酸（11）、对羟基苯甲酸（12）、3,4 - 二羟基苯甲酸（13）。
化合物3 - 9、11 - 13首次从该植物中分离得到。
