Clinical Cardiology, Thrombosis Center, University Hospital, 35128 Padova, Italy.
J Thromb Haemost. 2009 Oct;7(10):1737-40. doi: 10.1111/j.1538-7836.2009.03555.x. Epub 2009 Jul 17.
One of the conclusions of the subcommittee meeting on Lupus Anticoagulant/Phospholipid dependent antibodies, held in Geneva on 2007, was the need to update the guidelines on Lupus Anticoagulant (LA) detection. Particular emphasis was given to several aspects discussed in this official communication. A new paragraph is dedicated to the patient selection, and aims to minimize inappropriate requests for LA testing. Modalities for blood collection and processing are fully delineated and the choice of tests is limited to dRVVT and a sensitive aPTT. Calculation of cut-off values for each diagnostic step are clearly stated. A final paragraph reports the interpretation of the results in general and in particular situations.
2007 年在日内瓦举行的狼疮抗凝物/磷脂相关抗体小组委员会会议的结论之一，是需要更新狼疮抗凝物（LA）检测指南。本官方通讯特别强调了几个方面的讨论。新的段落专门用于患者选择，并旨在尽量减少对 LA 检测的不当要求。充分描述了血液采集和处理的方式，并且选择的检测方法仅限于 dRVVT 和敏感的 aPTT。明确规定了每个诊断步骤的截止值计算。最后一段报告了一般情况下和特殊情况下的结果解释。
