Department of Chemical Engineering, National Technical University of Athens, 15780 Athens, Greece.
Division of Removable Prosthodontics, University of Athens, 11527 Athens, Greece.
J Biomed Mater Res B Appl Biomater. 2009 Nov;91(2):964-974. doi: 10.1002/jbm.b.31482.
Facial prostheses deteriorate in a service environment primary due to exposition to various environmental factors, including sebaceous oils (sebum) and perspiration.
This study investigated the physical properties of an experimental, facial prosthetic after immersion for 6 months in simulated sebum, and perspiration at 37 degrees C.
Chlorinated polyethylene (CPE) specimens were immersed in simulated perspiration as well as in sebum. Compression tests were conducted on a Zwick testing machine. Shore A hardness measurements were carried out in a CV digital Shore A durometer. Melting and glass transition temperatures were evaluated with a differential scanning calorimeter. Weight changes were measured and color changes were determined in the CIE LAB system using a MiniScan XE spectrophotometer. Simple mathematical models were developed to correlate the measured properties with immersion time. The data were also subjected to analyses of variance (ANOVA) and the Tukey multiple range tests at a level of alpha = 0.05.
Specimens immersed in perspiration became harder due to facilitation of the propagation of cross-linking reaction that probably occurred during aging of the CPE samples. Some weight increase was observed for the specimens immersed into the aqueous solutions, whereas for those immersed in sebum, weight loss was recorded, probably because of extraction of some compounds. The color change was higher for the specimens immersed in sebum than that corresponding to simulated perspiration.
The chlorinated polyethylene specimens aged for a period, which simulates 1.5 years of clinical service1, showed significant deformations in their physical properties.
面部假体在使用环境中会恶化，主要是由于暴露于各种环境因素，包括皮脂油（皮脂）和汗液。
本研究调查了在 37°C 下模拟皮脂和汗液中浸泡 6 个月的实验性面部假体的物理性能。
将氯化聚乙烯（CPE）标本浸入模拟汗液和皮脂中。在 Zwick 试验机上进行压缩试验。在 CV 数字 Shore A 硬度计上进行肖氏 A 硬度测量。使用差示扫描量热仪评估熔融和玻璃化转变温度。测量重量变化，并使用 MiniScan XE 分光光度计在 CIE LAB 系统中测定颜色变化。开发了简单的数学模型，将测量的性能与浸泡时间相关联。还对数据进行方差分析（ANOVA）和 Tukey 多重范围检验，置信水平为 0.05。
浸入汗液中的标本由于交联反应的传播得到促进而变得更硬，这可能是在 CPE 样品老化期间发生的。浸入水溶液中的标本观察到一些重量增加，而浸入皮脂中的标本则记录到重量损失，可能是由于一些化合物的提取。浸入皮脂中的标本的颜色变化高于对应于模拟汗液的颜色变化。
经过模拟临床服务 1.5 年的老化期后，氯化聚乙烯标本的物理性能发生了明显的变形。
