Department of Internal Medicine, Department of Immunology, Seoul National University College of Medicine, 28 Yongon-dong, Chongno-gu, Seoul 110-744, Korea.
Rheumatol Int. 2012 Aug;32(8):2465-70. doi: 10.1007/s00296-011-1993-9. Epub 2011 Jul 19.
The aims of the present study were to determine the correlation between durometer scores with modified Rodnan skin scores (MRSS), scleroderma symptoms, and physical functions. A total of 31 patients with systemic sclerosis (SSc, 16 diffuse and 15 limited type) were enrolled in this study. Skin involvement was measured using a durometer and MRSS. Health assessment questionnaire (HAQ) disability indices, Keitel function test (KTF) scores, grip strengths, and scleroderma-visual analog scale (scleroderma-VAS) scores were measured. The correlations between durometer scores with MRSS, HAQ disability indices, and scleroderma-VAS scores were assessed. Durometer scores correlated well with MRSS at fingers, hands, forearms, upper arms, thighs, and feet, but poorly correlated with MRSS at the chest, abdomen, and lower legs. Total durometer scores correlated well with MRSS (r = 0.537, P = 0.002) and KTF scores (r = 0.608, P < 0.001), but poorly correlated with HAQ disability indices (r = 0.202, P = 0.276), and individual scleroderma-VAS scores. Durometer-measured skin hardnesses were found to correlate well with the MRSS scores of fingers, hands, forearms, upper arms, thighs, and feet. The authors suggest that these skin sites should be included when durometer measurements are made in systemic sclerosis.
本研究旨在确定硬度计评分与改良 Rodnan 皮肤评分（MRSS）、硬皮病症状和身体功能之间的相关性。共纳入 31 例系统性硬化症（SSc，16 例弥漫性和 15 例局限性）患者。采用硬度计和 MRSS 测量皮肤受累情况。采用健康评估问卷（HAQ）残疾指数、Keitel 功能测试（KTF）评分、握力和硬皮病视觉模拟评分（scleroderma-VAS）评估。评估了硬度计评分与 MRSS、HAQ 残疾指数和 scleroderma-VAS 评分之间的相关性。硬度计评分与手指、手、前臂、上臂、大腿和足部的 MRSS 相关性较好，但与胸部、腹部和小腿的 MRSS 相关性较差。总硬度计评分与 MRSS（r = 0.537，P = 0.002）和 KTF 评分（r = 0.608，P < 0.001）相关性较好，但与 HAQ 残疾指数（r = 0.202，P = 0.276）和个别 scleroderma-VAS 评分相关性较差。硬度计测量的皮肤硬度与手指、手、前臂、上臂、大腿和足部的 MRSS 评分相关性较好。作者建议在系统性硬化症中进行硬度计测量时，应包括这些皮肤部位。
