Bisiacchi Patrizia Silvia, Mento Giovanni, Suppiej Agnese
Department of General Psychology, University of Padova, Padova, Italy.
Biol Psychol. 2009 Oct;82(2):176-85. doi: 10.1016/j.biopsycho.2009.07.005. Epub 2009 Jul 22.
The aim of this study was to investigate the effects of gestational age on the auditory event-related potentials (AERPs) in preterm newborns of extremely low (23-29 weeks, N=20) and low gestational age (30-34 weeks, N=19). All subjects were tested at the same post-conceptional age of 35 weeks. An auditory oddball paradigm was used with frequently occurring "standard" tones at 1000 Hz and rarely occurring "deviant" tones at 2000 Hz. Newborns of less than 30 gestational weeks showed smaller AERPs responses (P1i, N2i and mismatch response) than the older ones. Our results suggest the role of gestational age as the main factor explaining cortical functioning at this early age.
本研究的目的是调查胎龄对极早产儿（23 - 29周，N = 20）和低胎龄儿（30 - 34周，N = 19）听觉事件相关电位（AERP）的影响。所有受试者均在孕龄35周时进行测试。采用听觉oddball范式，频繁出现的1000Hz“标准”音调以及偶尔出现的2000Hz“偏差”音调。小于30孕周的新生儿AERP反应（P1i、N2i和失配反应）比年龄较大的新生儿小。我们的结果表明胎龄是解释这一年龄段皮质功能的主要因素。
