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Psychosis genetics: modeling the relationship between schizophrenia, bipolar disorder, and mixed (or "schizoaffective") psychoses.精神病遗传学:构建精神分裂症、双相情感障碍和混合型(或“分裂情感性”)精神病之间的关系模型。
Schizophr Bull. 2009 May;35(3):482-90. doi: 10.1093/schbul/sbp020. Epub 2009 Mar 27.
2
Investigating the association between neurocognition and psychosis in bipolar disorder: further evidence for the overlap with schizophrenia.双相情感障碍中神经认知与精神病性症状之间的关联研究:与精神分裂症重叠的进一步证据
Bipolar Disord. 2009 Mar;11(2):166-77. doi: 10.1111/j.1399-5618.2009.00663.x.
3
Neuropsychological performance as endophenotypes in extended schizophrenia families from the Central Valley of Costa Rica.在来自哥斯达黎加中央山谷的精神分裂症扩展家庭中,神经心理学表现作为内表型。
Psychiatr Genet. 2009 Feb;19(1):45-52. doi: 10.1097/YPG.0b013e3283202816.
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Executive and verbal working memory dysfunction in first-degree relatives of patients with bipolar disorder.双相情感障碍患者一级亲属的执行功能和言语工作记忆功能障碍。
Psychiatry Res. 2008 Dec 15;161(3):318-24. doi: 10.1016/j.psychres.2007.09.002. Epub 2008 Oct 31.
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Bridging the gap between schizophrenia and psychotic mood disorders: Relating neurocognitive deficits to psychopathology.弥合精神分裂症与精神病性心境障碍之间的差距:将神经认知缺陷与精神病理学联系起来。
Schizophr Res. 2009 Jan;107(1):69-75. doi: 10.1016/j.schres.2008.07.014. Epub 2008 Sep 10.
6
Cognitive endophenotypes of bipolar disorder: a meta-analysis of neuropsychological deficits in euthymic patients and their first-degree relatives.双相情感障碍的认知内表型:对心境正常患者及其一级亲属神经心理学缺陷的荟萃分析。
J Affect Disord. 2009 Feb;113(1-2):1-20. doi: 10.1016/j.jad.2008.06.009. Epub 2008 Aug 5.
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1-year follow-up study of cognitive function in first-episode non-affective psychosis.首发非情感性精神病认知功能的1年随访研究
Schizophr Res. 2008 Sep;104(1-3):165-74. doi: 10.1016/j.schres.2008.05.020. Epub 2008 Jul 16.
8
Neurocognitive endophenotypes (endophenocognitypes) from studies of relatives of bipolar disorder subjects: a systematic review.双相情感障碍患者亲属研究中的神经认知内表型(内表型认知类型):一项系统综述。
Neurosci Biobehav Rev. 2008 Oct;32(8):1426-38. doi: 10.1016/j.neubiorev.2008.05.019. Epub 2008 May 23.
9
Shared neurocognitive dysfunctions in young offspring at extreme risk for schizophrenia or bipolar disorder in eastern quebec multigenerational families.魁北克东部多代家庭中患精神分裂症或双相情感障碍极高风险的年幼后代的共享神经认知功能障碍。
Schizophr Bull. 2009 Sep;35(5):919-30. doi: 10.1093/schbul/sbn058. Epub 2008 Jun 11.
10
Neuropsychological function and dysfunction in schizophrenia and psychotic affective disorders.精神分裂症和精神性情感障碍中的神经心理功能与功能障碍。
Schizophr Bull. 2009 Sep;35(5):1022-9. doi: 10.1093/schbul/sbn044. Epub 2008 May 20.

精神分裂症和主要心境障碍中的神经心理学异常:异同点

Neuropsychological abnormalities in schizophrenia and major mood disorders: similarities and differences.

作者信息

Barch Deanna M

机构信息

Department of Psychology, Washington University in St. Louis, Box 1125, One Brookings Drive, St. Louis, MO 63130, USA.

出版信息

Curr Psychiatry Rep. 2009 Aug;11(4):313-9. doi: 10.1007/s11920-009-0045-6.

DOI:10.1007/s11920-009-0045-6
PMID:19635240
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3836606/
Abstract

The past 20 years have been witness to a growing knowledge base of research highlighting the critical importance of cognition in understanding functional status and outcome in schizophrenia. This work has led to an increased emphasis on identifying and evaluating treatments that enhance cognition in schizophrenia, with the hope that this would translate into a better quality of life and improved outcome for patients. At the same time, this research has raised new questions about the specificity of cognitive impairments to schizophrenia and the degree to which similar cognitive impairments may be present in other disorders that can involve psychotic symptoms (eg, schizoaffective disorder, bipolar disorder, and psychotic major depression). This article provides a brief overview of work comparing cognitive function across the nonaffective and affective psychoses and highlights areas of similarity and dissimilarity in the role cognition plays in these disorders.

摘要

在过去20年里,越来越多的研究知识库表明,认知在理解精神分裂症的功能状态和预后方面至关重要。这项工作使得人们更加重视识别和评估能够改善精神分裂症认知功能的治疗方法,期望这能转化为患者更高的生活质量和更好的预后。与此同时,这项研究也引发了关于精神分裂症认知障碍特异性的新问题,以及在其他可能出现精神病性症状的疾病(如精神分裂症性情感障碍、双相情感障碍和伴有精神病性症状的重度抑郁症)中,类似认知障碍的存在程度。本文简要概述了比较非情感性和情感性精神病认知功能的研究,并突出了认知在这些疾病中所起作用的异同点。