Zhao Lingzhou, Chu Paul K, Zhang Yumei, Wu Zhifen
School of Stomatology, The Fourth Military Medical University, Xi'an 710072, People's Republic of China.
J Biomed Mater Res B Appl Biomater. 2009 Oct;91(1):470-80. doi: 10.1002/jbm.b.31463.
Titanium and titanium alloys are key biomedical materials because of their good biocompatibility and mechanical properties. Nevertheless, infection on and around titanium implants still remains a problem which is usually difficult to treat and may lead to eventual implant removal. As a result, preventive measures are necessary to mitigate implant-frelated infection. One important strategy is to render the implant surface antibacterial by impeding the formation of a biofilm. A number of approaches have been proposed for this purpose and they are reviewed in this article.
钛及钛合金因其良好的生物相容性和机械性能而成为关键的生物医学材料。然而,钛植入物及其周围的感染仍然是一个问题,通常难以治疗,可能最终导致植入物取出。因此,有必要采取预防措施来减轻与植入物相关的感染。一个重要的策略是通过阻止生物膜的形成使植入物表面具有抗菌性。为此已经提出了许多方法,本文将对这些方法进行综述。