Abbaszadeh Shahin, Taheri Saeed, Nourbala Mohammad Hossein
Dr. Taheri Medical Research Group, Baqiyatallah Research Center for Gastroenterology and Liver diseases, Baqiyatallah Hospital, Mullasadra Ave, Tehran 1435915371, Iran.
Adv Urol. 2009;2009:231861. doi: 10.1155/2009/231861. Epub 2009 Jul 20.
In this study we report our experience with microhematuria and its relation with bladder tumors in Iranian women.
Overall 249 women were evaluated. Microscopic hematuria was defined as three or more red blood cells per high-power field on at least two different occasions. Patients with a history of gross hematuria or coagulation disorders, having organic diseases, urinary stones, urinary tract infections, nephrological diseases, and local lesions such as urethral caruncle were excluded from the study population. Final diagnosis of malignant tumors was done with cystoscopy and biopsy specimen pathological assessment in all cases.
Age for the study population was 49.7 +/- 11.8 years. 95 (38%) of patients were identified during routine check up and presenting symptoms in other patients were frequency, dysuria, stress urge incontinence, urge incontinence, feeling of incomplete urine emptying, and flunk pain, respectively. Finally, 7 (2.8%) of study subjects were confirmed as having bladder tumors. One of tumor cases was diagnosed 24 months after initial assessments. Patients with bladder tumor were significantly older; more frequently had diverticulum in their bladder wall (P < .05).
Female microscopic hematuria is relevant and deserves evaluations, especially in elderly patients. Patients whose reason for microhematuria would not be diagnosed at the initial evaluations should be followed.
在本研究中，我们报告了伊朗女性镜下血尿的情况及其与膀胱肿瘤的关系。
共评估了249名女性。镜下血尿定义为在至少两次不同检查中，每高倍视野有三个或更多红细胞。有肉眼血尿病史或凝血障碍、患有器质性疾病、尿路结石、尿路感染、肾脏疾病以及尿道肉阜等局部病变的患者被排除在研究人群之外。所有病例均通过膀胱镜检查和活检标本病理评估做出恶性肿瘤的最终诊断。
研究人群的年龄为49.7±11.8岁。95名（38%）患者在常规检查中被发现，其他患者出现的症状分别为尿频、排尿困难、压力性尿失禁、急迫性尿失禁、尿不尽感和耻骨上区疼痛。最终，7名（2.8%）研究对象被确诊患有膀胱肿瘤。其中1例肿瘤病例在初次评估24个月后被诊断出来。患有膀胱肿瘤的患者年龄明显更大；膀胱壁有憩室的情况更常见（P<.05）。
女性镜下血尿具有相关性，值得评估，尤其是在老年患者中。对于初次评估时镜下血尿原因未明确诊断的患者应进行随访。
