Day Emily S, Morton Jennifer G, West Jennifer L
Department of Bioengineering, Rice University, 6100 Main Street, MS 142, Houston, TX 77005, USA.
J Biomech Eng. 2009 Jul;131(7):074001. doi: 10.1115/1.3156800.
Advances in nanotechnology are enabling many new diagnostic and therapeutic approaches in cancer. In this review, examples where nanoparticles are employed to induce localized heating within tumors are explored. Approaches to nanoparticle-mediated thermal therapy include absorption of infrared light, radio frequency ablation, and magnetically-induced heating. These approaches have demonstrated high efficacy in animal models, and two are already in human clinical trials.
纳米技术的进步正在催生许多针对癌症的新型诊断和治疗方法。在本综述中，我们探讨了利用纳米颗粒在肿瘤内诱导局部加热的实例。纳米颗粒介导的热疗方法包括红外光吸收、射频消融和磁诱导加热。这些方法在动物模型中已显示出高效性，并且其中两种已进入人体临床试验阶段。
