Desai Mihir M, Berger Andre K, Brandina Ricardo, Aron Monish, Irwin Brian H, Canes David, Desai Mahesh R, Rao Pradeep P, Sotelo Rene, Stein Robert, Gill Inderbir S
Department of Urology, Glickman Urological and Kidney Institute, Cleveland Clinic, Cleveland, Ohio 44196, USA.
Urology. 2009 Oct;74(4):805-12. doi: 10.1016/j.urology.2009.02.083. Epub 2009 Jul 30.
To report our initial experience with laparoendoscopic single-site (LESS) surgery in 100 patients in urology.
Between October 2007 and December 2008, we performed LESS urologic procedures in 100 patients for various indications. These included nephrectomy (N = 34; simple 14, radical 3, donor 17), nephroureterectomy (N = 2), partial nephrectomy (N = 6), pyeloplasty (N = 17), transvesical simple prostatectomy (N = 32), and others (N = 9). Data were prospectively collected in a database approved by the Institutional Review Board. All procedures were performed using a novel single-port device (r-Port) and a varying combination of standard and specialized bent/articulating laparoscopic instruments. Robotic assistance was used to perform LESS pyeloplasty (N = 2) and simple prostatectomy (N = 1). In addition to standard perioperative data, we obtained data on postdischarge analgesia requirements, time to complete convalescence, and time to return to work.
In the study period, LESS procedures accounted for 15% of all laparoscopic cases by the authors for similar indications. Conversion to standard multiport laparoscopy was necessary in 3 cases, addition of a single 5-mm port was necessary in 3 cases, and conversion to open surgery was necessary in 4 cases. On death occurred following simple prostatectomy in a Jehovah's Witness due to patient refusal to accept transfusion following hemorrhage. Intra- and postoperative complications occurred in 5 and 9 cases, respectively. Mean operative time was 145, 230, 236, and 113 minutes and hospital stay was 2, 2.9, 2, and 3 days for simple nephrectomy, donor nephrectomy, pyeloplasty, and simple prostatectomy, respectively.
The LESS surgery is technically feasible for a variety of ablative and reconstructive applications in urology. With proper patient selection, conversion and complications rates are low. Improvement in instrumentation and technology is likely to expand the role of LESS in minimally invasive urology.
报告我们在100例泌尿外科患者中开展经自然腔道内镜手术(LESS)的初步经验。
2007年10月至2008年12月期间,我们对100例因各种适应证而接受LESS泌尿外科手术的患者进行了手术。这些手术包括肾切除术(n = 34;单纯性肾切除术14例、根治性肾切除术3例、供体肾切除术17例)、肾输尿管切除术(n = 2)、部分肾切除术(n = 6)、肾盂成形术(n = 17)、经膀胱单纯前列腺切除术(n = 32)以及其他手术(n = 9)。数据前瞻性地收集于经机构审查委员会批准的数据库中。所有手术均使用一种新型单孔装置(r-Port)以及标准和专用的弯曲/关节腹腔镜器械的不同组合进行。机器人辅助用于开展LESS肾盂成形术(n = 2)和单纯前列腺切除术(n = 1)。除了标准的围手术期数据外,我们还获取了出院后镇痛需求、完全康复时间以及恢复工作时间的数据。
在研究期间,LESS手术占作者针对类似适应证所开展的所有腹腔镜手术的15%。3例患者需要转为标准多孔腹腔镜手术,3例患者需要增加一个5毫米的单孔,4例患者需要转为开放手术。1例耶和华见证会信徒在接受单纯前列腺切除术后死亡,原因是患者在出血后拒绝接受输血。术中及术后并发症分别发生在5例和9例患者中。单纯肾切除术、供体肾切除术、肾盂成形术和单纯前列腺切除术的平均手术时间分别为145、230、236和113分钟,住院时间分别为2、2.9、2和3天。
LESS手术在泌尿外科的各种切除和重建应用中在技术上是可行的。通过适当的患者选择,中转率和并发症发生率较低。器械和技术的改进可能会扩大LESS在微创泌尿外科中的作用。