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同期肺癌切除术与肺减容手术

Concomitant lung cancer resection and lung volume reduction surgery.

作者信息

Choong Cliff K, Mahesh Balakrishnan, Patterson G Alexander, Cooper Joel D

机构信息

Papworth Hospital NHS Foundation Trust, Cambridge, UK.

出版信息

Thorac Surg Clin. 2009 May;19(2):209-16. doi: 10.1016/j.thorsurg.2009.04.004.

Abstract

Patients who are offered concomitant surgery are highly selected and must satisfy the strict criteria set out for both LVRS and cancer surgery. Several evaluative processes have been reported for the selection of suitable patients. These various evaluative processes, together with the physical condition of the patient and the surgeon's experience, help to best select patients suitable for combined surgical resection. Several intraoperative strategies are available for dealing with a patient who has concomitant lung cancer and severe emphysema. The choice of technique depends on the location and size of the tumor, the severity and distribution of the emphysema, and the surgeon's experience and preference. Lung volume reduction surgery in well-selected patients who have severe emphysema results in postoperative improvement of symptoms and measured pulmonary function. The combination of lung cancer resection with LVRS offers selected patients who have concomitant early lung cancer and severe emphysema the opportunity to undergo resection of their cancer with improvement rather than further reduction in their pulmonary function. By traditional criteria these patients would otherwise be considered unsuitable surgical candidates because of the limited pulmonary function.

摘要

接受同期手术的患者经过严格筛选,必须满足为肺减容术(LVRS)和癌症手术所设定的严格标准。已有多项评估流程用于筛选合适的患者。这些不同的评估流程,连同患者的身体状况和外科医生的经验,有助于最佳地选择适合联合手术切除的患者。对于患有同期肺癌和重度肺气肿的患者,有几种术中策略可供采用。技术的选择取决于肿瘤的位置和大小、肺气肿的严重程度和分布情况,以及外科医生的经验和偏好。在精心挑选的重度肺气肿患者中进行肺减容手术可使术后症状得到改善,并使肺功能指标有所提高。肺癌切除术与肺减容术相结合,为患有同期早期肺癌和重度肺气肿的特定患者提供了机会,使其能够接受癌症切除术,同时肺功能得到改善而非进一步下降。按照传统标准,这些患者由于肺功能有限,原本会被认为是不适合手术的候选人。

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