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Selective inhibition of cyclic nucleotide phosphodiesterases by analogues of 1-methyl-3-isobutylxanthine.

作者信息

Kramer G L, Garst J E, Mitchel S S, Wells J N

出版信息

Biochemistry. 1977 Jul 26;16(15):3316-21. doi: 10.1021/bi00634a006.

DOI:10.1021/bi00634a006
PMID:196632
Abstract
摘要

相似文献

1
Selective inhibition of cyclic nucleotide phosphodiesterases by analogues of 1-methyl-3-isobutylxanthine.
Biochemistry. 1977 Jul 26;16(15):3316-21. doi: 10.1021/bi00634a006.
2
Methylxanthine inhibitors of phosphodiesterases.磷酸二酯酶的甲基黄嘌呤抑制剂。
Methods Enzymol. 1988;159:489-96. doi: 10.1016/0076-6879(88)59048-1.
3
Phosphodiesterase inhibitors as tools in cyclic nucleotide research: a precautionary comment.磷酸二酯酶抑制剂作为环核苷酸研究工具:一则预防性评论。
Mol Cell Endocrinol. 1981 Jul;23(1):1-9. doi: 10.1016/0303-7207(81)90112-x.
4
The effects of alkylated xanthines on cyclic AMP accumulation in dog thyroid slices exposed to carbamylcholine.烷基化黄嘌呤对暴露于氨甲酰胆碱的犬甲状腺切片中环磷酸腺苷积累的影响。
Mol Pharmacol. 1984 Mar;25(2):261-6.
5
Selective phosphodiesterase inhibition and alterations of cardiac function by alkylated xanthines.
Mol Pharmacol. 1981 Jul;20(1):179-89.
6
PDE4 inhibitors: new xanthine analogues.磷酸二酯酶4抑制剂:新型黄嘌呤类似物
Bioorg Med Chem Lett. 1998 Oct 20;8(20):2925-30. doi: 10.1016/s0960-894x(98)00524-1.
7
Inhibition of a high molecular weight cyclic 3',5'-nucleotide phosphodiesterase isolated from rat liver.
Biochem Pharmacol. 1976 Jan;25(1):97-9. doi: 10.1016/0006-2952(76)90179-9.
8
Effect of some phosphodiesterase inhibitors on two different preparations of adenosine 3',5'-monophosphate phosphodiesterase.某些磷酸二酯酶抑制剂对两种不同制剂的3',5'-环磷酸腺苷磷酸二酯酶的作用。
Experientia. 1975 Aug 15;31(8):883-4. doi: 10.1007/BF02358828.
9
Tissue selective inhibition of cyclic nucleotide phosphodiesterase by denbufylline.登布茶碱对环核苷酸磷酸二酯酶的组织选择性抑制作用。
Arzneimittelforschung. 1989 Jun;39(6):665-7.
10
Selective inhibitors of specific phosphodiesterases in intact adipocytes.
Methods Enzymol. 1988;159:504-20. doi: 10.1016/0076-6879(88)59050-x.

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Stimulation of electro-olfactogram responses in the main olfactory epithelia by airflow depends on the type 3 adenylyl cyclase.气流刺激主要嗅觉上皮的电嗅觉图反应依赖于 III 型腺苷酸环化酶。
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Cyclic nucleotide phosphodiesterases as targets for treatment of haematological malignancies.环核苷酸磷酸二酯酶作为血液系统恶性肿瘤的治疗靶点
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Inhibition of myofibroblastic transformation of cultured rat hepatic stellate cells by methylxanthines and dibutyryl cAMP.
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Strategic approaches to drug design. II. Modelling studies on phosphodiesterase substrates and inhibitors.药物设计的策略方法。II. 磷酸二酯酶底物和抑制剂的建模研究。
J Comput Aided Mol Des. 1987 Jul;1(2):97-119. doi: 10.1007/BF01676955.
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The use of oxyhaemoglobin to explore the events underlying inhibition of platelet aggregation induced by NO or NO-donors.利用氧合血红蛋白探究一氧化氮或一氧化氮供体诱导血小板聚集抑制作用背后的机制。
Br J Pharmacol. 1990 Dec;101(4):991-5. doi: 10.1111/j.1476-5381.1990.tb14194.x.
6
Flavonoid compounds are potent inhibitors of cyclic AMP phosphodiesterase.
Experientia. 1978 Aug 15;34(8):1054-5. doi: 10.1007/BF01915343.