Flavonoid compounds are potent inhibitors of cyclic AMP phosphodiesterase.
作者信息
Beretz A, Anton R, Stoclet J C
出版信息
Experientia. 1978 Aug 15;34(8):1054-5. doi: 10.1007/BF01915343.
PMID:212288
Abstract
The inhibitory activity of 19 flavonoid molecules on cyclic AMP breakdown by a commercial beef heart phosphodiesterase preparation is reported. 7 compounds are active in the micromolar range, 2 of which have a potency equivalent to that of papaverine. Some structure activity relationships are drawn.
摘要
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