Gaeta G B, Rapicetta M, Sardaro C, Chionne P, Costantino A, Giusti G
Clinical Malattie Infettive, 1. Facoltà di Medicina, Università di Napoli, Italy.
Ital J Gastroenterol. 1990 Dec;22(6):350-1.
The prevalence of anti-HCV and anti-HBV antibodies was investigated in a series of 77 adult patients with HBsAg negative, non autoimmune chronic liver disease. Anti-HCV were found in 68% and anti-HBc in 71% of the cases; 68% of the patients carried both antibodies. There was no difference in the proportion of anti-HBc positive cases between the anti-HCV positive or negative patients. The intense circulation of HBV infection in Southern Italy during the past decades might explain the high percentage of subjects with anti-HBc. Whether the co-occurrence of HCV and HBV infection may influence the natural history of the liver disease, remains to be established.
在一系列77例HBsAg阴性、非自身免疫性慢性肝病的成年患者中，对丙肝抗体（anti-HCV）和乙肝抗体（anti-HBV）的流行情况进行了调查。68%的病例检测到anti-HCV，71%的病例检测到anti-HBc；68%的患者同时携带这两种抗体。anti-HCV阳性或阴性患者中anti-HBc阳性病例的比例没有差异。过去几十年间，意大利南部乙肝感染的广泛传播可能解释了anti-HBc阳性受试者的高比例。丙肝和乙肝感染的同时发生是否会影响肝病的自然病程，仍有待确定。
