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Posterior capsule opacification and neovascularization treated with intravitreal bevacizumab and Nd:YAG capsulotomy.

作者信息

Sánchez-Castro Grimelda Yuriana, Hitos-Fájer Alejandra, Mendoza-Schuster Erick, Velez-Montoya Raul, Velasco-Barona Cecilio Francisco

机构信息

Asociación para Evitar la Ceguera en México. Hospital "Dr. Luis Sánchez Bulnes", México, D.F. Ophthalmology Department - Anterior Segment, Mexico.

出版信息

Clin Ophthalmol. 2008 Sep;2(3):657-60. doi: 10.2147/opth.s2686.

DOI:10.2147/opth.s2686
PMID:19668770
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC2694023/
Abstract

We reported a 75-year-old diabetic man, who developed opacification and neovascularization of the posterior capsule after extracapsular cataract extraction and posterior chamber intraocular lens implantation. The patient was treated with two injections of 2.5 mg of intravitreal bevacizumab. The treatment produced an important regression of the posterior capsular new vessels, allowing us to perform a successful Nd:YAG capsulotomy, clearing the visual axis and improving the visualization of the posterior pole. Even though, best corrected visual acuity was 20/200 due to diabetic macular edema.

摘要
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3b2c/2694023/b675f63132e9/co-2-657f3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3b2c/2694023/fb1c91187931/co-2-657f1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3b2c/2694023/84d9f7cada7e/co-2-657f2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3b2c/2694023/b675f63132e9/co-2-657f3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3b2c/2694023/fb1c91187931/co-2-657f1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3b2c/2694023/84d9f7cada7e/co-2-657f2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3b2c/2694023/b675f63132e9/co-2-657f3.jpg

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本文引用的文献

1
Photodynamic therapy for posterior capsule neovascularization.后囊膜新生血管的光动力疗法。
J Cataract Refract Surg. 2007 Jun;33(6):1131-2. doi: 10.1016/j.jcrs.2007.02.025.
2
Regression of neovascular posterior capsule vessels by intravitreal bevacizumab.玻璃体内注射贝伐单抗使新生血管性后囊膜血管消退。
J Cataract Refract Surg. 2007 Jun;33(6):1113-5. doi: 10.1016/j.jcrs.2007.01.040.
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Pharmacokinetics of intravitreal bevacizumab (Avastin).玻璃体内注射贝伐单抗（阿瓦斯汀）的药代动力学
Clin Ophthalmol. 2008 Sep;2(3):i.
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The management of diabetic eye disease in the setting of cataract surgery.白内障手术背景下糖尿病眼病的管理
Curr Opin Ophthalmol. 2007 Feb;18(1):13-8. doi: 10.1097/ICU.0b013e32801129fc.
5
Intravitreal bevacizumab (Avastin) in the treatment of proliferative diabetic retinopathy.玻璃体内注射贝伐单抗（阿瓦斯汀）治疗增殖性糖尿病视网膜病变。
Ophthalmology. 2006 Oct;113(10):1695.e1-15. doi: 10.1016/j.ophtha.2006.05.064.
6
Posterior capsule opacification after cataract surgery in patients with diabetes mellitus.糖尿病患者白内障手术后的后囊膜混浊
J Cataract Refract Surg. 2006 Jul;32(7):1184-7. doi: 10.1016/j.jcrs.2006.01.100.
7
Cataract surgery and postoperative complications in diabetic patients.糖尿病患者的白内障手术及术后并发症
Coll Antropol. 2005;29 Suppl 1:55-8.
8
Occurrence and progression of diabetic retinopathy after phacoemulsification cataract surgery.白内障超声乳化吸除术后糖尿病视网膜病变的发生与进展
J Cataract Refract Surg. 2004 Feb;30(2):428-32. doi: 10.1016/S0886-3350(03)00579-0.
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A randomized trial of bevacizumab, an anti-vascular endothelial growth factor antibody, for metastatic renal cancer.一项关于抗血管内皮生长因子抗体贝伐单抗用于转移性肾癌的随机试验。
N Engl J Med. 2003 Jul 31;349(5):427-34. doi: 10.1056/NEJMoa021491.
10
Posterior capsule opacification after cataract surgery in patients with diabetes mellitus.
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