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应用 N-2-正丁基氰基丙烯酸酯选择性动脉栓塞治疗骨骼 36 例骨囊肿动脉瘤。

Selective arterial embolization of 36 aneurysmal bone cysts of the skeleton with N-2-butyl cyanoacrylate.

机构信息

Department of Interventional Angiographic Radiology, Rizzoli Orthopaedic Institute, Bologna, Italy.

出版信息

Skeletal Radiol. 2010 Feb;39(2):161-7. doi: 10.1007/s00256-009-0757-z.

DOI:10.1007/s00256-009-0757-z
PMID:19669138
Abstract

BACKGROUND

Aneurysmal bone cyst (ABC) is a lytic benign bone lesion representing about 1% of all primary bone tumors. The lesion causes pain and swelling, which are generally present for less than 3 months.

METHODS

From April 2003 to April 2008 36 patients affected by aneurysmal bone cysts were treated by selective arterial embolization with N-2-butyl cyanoacrylate. The study population comprised 20 male and 16 female patients with an age range of 3.3-60.8 years. Nine lesions were localized in the appendicular skeleton (1 in the upper and 8 in the lower limb), 4 in the thoracic cage (1 rib lesion and 3 scapular lesions), 17 in the pelvis and 6 in the spine (1 thoracic and 5 sacral localizations).

RESULTS

A total of 55 embolizations were performed: in 22 cases (61%) only one embolization was needed, whilst two embolizations were necessary in 9 cases (25%) and 3 in the remaining 5 patients (14%). The treatment was effective in 32 patients (94% ): follow-up was 0.9-5 years. In one patient, previously surgically treated, only the cyanoacrylate embolization turned out to be useful for healing the lesion. Another 7 patients underwent surgery during the study period. In the 55 procedures we performed we had 3 complications (5%): 2 cases of skin necrosis and 1 of transient paresis.

CONCLUSIONS

Arterial embolization with cyanoacrylate may be the treatment of choice for aneurysmal bone cysts. Embolization is a less invasive, lower cost, simpler procedure than surgery and is easily repeatable.

摘要

背景

动脉瘤样骨囊肿(ABC)是一种溶骨性良性骨病变,约占所有原发性骨肿瘤的 1%。病变引起疼痛和肿胀,一般持续不到 3 个月。

方法

2003 年 4 月至 2008 年 4 月,36 例动脉瘤样骨囊肿患者采用 N-2-丁基氰基丙烯酸酯选择性动脉栓塞治疗。研究人群包括 20 名男性和 16 名女性,年龄 3.3-60.8 岁。9 处病变位于四肢(1 处在上肢,8 处在下肢),4 处位于胸廓(1 处肋骨病变,3 处肩胛骨病变),17 处位于骨盆,6 处位于脊柱(1 处胸椎,5 处骶骨定位)。

结果

共进行了 55 次栓塞术:22 例(61%)仅需一次栓塞,9 例(25%)需两次栓塞,5 例(14%)需 3 次栓塞。32 例(94%)患者治疗有效:随访 0.9-5 年。在 1 例先前手术治疗的患者中,只有氰基丙烯酸酯栓塞术对愈合病变有效。研究期间还有另外 7 例患者接受了手术。在我们进行的 55 次手术中,有 3 例出现并发症(5%):2 例皮肤坏死,1 例短暂性瘫痪。

结论

氰基丙烯酸酯动脉栓塞术可能是动脉瘤样骨囊肿的首选治疗方法。栓塞术比手术创伤小、成本低、操作简单,且易于重复。

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