Cucé L C, Belda Júnior W, Ribeiro E B
Departamento de Dermatologia da Faculdade de Medicina da Universidade de São Paulo, Brasil.
Rev Inst Med Trop Sao Paulo. 1990 May-Jun;32(3):181-4.
The authors present the results obtained in the treatment of pityriasis versicolor with Itraconazole, comparing two schemes of treatment, in an open trial: 200 mg daily, for 5 and 7 days. The clinical diagnosis was confirmed by Wood's light and mycologically, by direct examination. The patients were controlled 21 and 35 days after beginning the treatment. The evaluation of the results showed that both schemes were effective. At the second control, there was clinical and mycologic cure in 90% of the patients from the 5-day group and in 95% of the patients from the 7-day group. The tolerance was good: 2 patients from the 7-day group and 1 patient from the 5-day group showed side-effects. Since there was no significant difference between the two schemes of treatment, the authors recommend the shortest one, that is, 200 mg daily for 5 days.
作者在一项开放性试验中展示了使用伊曲康唑治疗花斑糠疹所取得的结果，比较了两种治疗方案：每日200毫克，持续5天和7天。临床诊断通过伍德灯检查确认，真菌学诊断通过直接检查确认。在开始治疗后的21天和35天对患者进行了随访。结果评估显示两种方案均有效。在第二次随访时，5天治疗组90%的患者以及7天治疗组95%的患者实现了临床和真菌学治愈。耐受性良好：7天治疗组有2名患者、5天治疗组有1名患者出现了副作用。由于两种治疗方案之间没有显著差异，作者推荐使用最短的方案，即每日200毫克，持续5天。
