由一个星形胶质细胞、一个神经元和一个中间神经元组成的最小神经模型的动力学。
Dynamics of a minimal neural model consisting of an astrocyte, a neuron, and an interneuron.
作者信息
Di Garbo Angelo
机构信息
Istituto di Biofisica CNR, 56124, Pisa, Italy.
出版信息
J Biol Phys. 2009 Oct;35(4):361-82. doi: 10.1007/s10867-009-9143-2. Epub 2009 May 7.
Abstract
In this paper, a biophysical neural network model consisting of a pyramidal neuron, an interneuron, and the astrocyte is studied. The corresponding dynamical properties are mainly investigated by using numerical simulations. The results show that the presence of the adenosine triphosphate and of the interneuron impacts the overall neural activity. It is shown that the fluxes of calcium through the cellular membrane strongly affect the modulation of the neural activity arising from the astrocyte.
摘要
本文研究了一个由锥体神经元、中间神经元和星形胶质细胞组成的生物物理神经网络模型。主要通过数值模拟来研究其相应的动力学特性。结果表明，三磷酸腺苷和中间神经元的存在会影响整体神经活动。研究表明，钙离子通过细胞膜的通量强烈影响星形胶质细胞产生的神经活动的调节。
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