Privalsky M L
Department of Microbiology, University of California, Davis 95616.
J Virol. 1990 Jan;64(1):463-6. doi: 10.1128/JVI.64.1.463-466.1990.
The v-erbA oncogene of avian erythroblastosis virus is derived from a cellular gene for a thyroid hormone (T4/T3 thyronine) receptor and encodes a DNA-binding protein found principally in the nucleus of the infected cell. I report here that a subpopulation of the v-erbA protein is glycosylated. The v-erbA protein, therefore, is another member of the newly recognized family of eucaryotic transcription factors and related polypeptides which are glycoproteins.
禽成红细胞增多症病毒的v-erbA癌基因源自一种甲状腺激素(T4/T3甲状腺素)受体的细胞基因,并编码一种主要存在于受感染细胞核中的DNA结合蛋白。我在此报告,v-erbA蛋白的一个亚群是糖基化的。因此,v-erbA蛋白是新确认的真核转录因子和相关糖蛋白多肽家族的另一个成员。