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体重减轻对肥胖相关疾病的影响。

Effects of weight-reduction on obesity-associated diseases.

作者信息

Liebermeister Hermann

机构信息

PVS Mosel/Saar, Neunkirchen, Germany.

出版信息

Ger Med Sci. 2003 Jul 1;1:Doc04.

PMID:19675702
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC2703231/
Abstract

Even moderate, but persistent weight-loss ameliorates most of the related diseases in obesity. Besides the consequences of the metabolic syndrome, this includes less well-known obesity-associated changes, such as impaired fertility, menstrual disorders, psychic changes, total leucocyte-count as a parameter of immunity and the impaired pulmonary function in asthma and sleep-apnoea. Life-expectancy is prolonged by diminution of visceral fat depots, whilst weight-loss by shrinking of fat-free body-mass seems to have a contrary effect.

摘要

即使是适度但持续的体重减轻也能改善肥胖症的大多数相关疾病。除了代谢综合征的后果外,这还包括一些不太为人所知的与肥胖相关的变化,如生育能力受损、月经紊乱、心理变化、作为免疫参数的白细胞总数以及哮喘和睡眠呼吸暂停患者的肺功能受损。通过减少内脏脂肪储存可延长预期寿命,而通过减少去脂体重来减轻体重似乎会产生相反的效果。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/cd5d/2703231/734624d219ae/GMS-01-04-t-001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/cd5d/2703231/734624d219ae/GMS-01-04-t-001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/cd5d/2703231/734624d219ae/GMS-01-04-t-001.jpg

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本文引用的文献

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Rational therapy for secondary amenorrhea.继发性闭经的合理治疗。
N Engl J Med. 1950 Sep 7;243(10):357-62. doi: 10.1056/NEJM195009072431001.
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Weight loss increases and fat loss decreases all-cause mortality rate: results from two independent cohort studies.体重减轻增加而脂肪减少降低全因死亡率:两项独立队列研究的结果。
Int J Obes Relat Metab Disord. 1999 Jun;23(6):603-11. doi: 10.1038/sj.ijo.0800875.
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Visceral adipose tissue: a critical review of intervention strategies.内脏脂肪组织:干预策略的批判性综述
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Effect on mortality and reinfarction of adding fruits and vegetables to a prudent diet in the Indian experiment of infarct survival (IEIS).在印度心肌梗死生存实验(IEIS)中,在合理饮食基础上增加水果和蔬菜对死亡率及再梗死的影响。
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