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自闭症谱系障碍成人的多项列表学习:与额叶损伤的相似之处还是关系处理能力下降的进一步证据?

Multiple list learning in adults with autism spectrum disorder: parallels with frontal lobe damage or further evidence of diminished relational processing?

机构信息

Department of Psychology, City University, London, UK.

出版信息

J Autism Dev Disord. 2010 Feb;40(2):179-87. doi: 10.1007/s10803-009-0845-x. Epub 2009 Aug 13.

DOI:10.1007/s10803-009-0845-x
PMID:19680798
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC2810365/
Abstract

To test the effects of providing relational cues at encoding and/or retrieval on multi-trial, multi-list free recall in adults with high-functioning autism spectrum disorder (ASD), 16 adults with ASD and 16 matched typical adults learned a first followed by a second categorised list of 24 words. Category labels were provided at encoding, retrieval, both or not at all. Both groups showed enhanced recall when labels were available during encoding or throughout the task. ASD individuals showed reduced recall of the second list and reduced clustering. Clustering and recall were correlated in both groups, which also showed similar levels of subjective organisation. The findings are discussed in relation to theories of frontal and medial temporal lobe contributions to memory in ASD.

摘要

为了检验在成人高功能自闭症谱系障碍(ASD)患者的多试、多列表自由回忆中,在编码和/或检索时提供关系线索对其的影响,16 名 ASD 患者和 16 名匹配的典型成年人学习了第一组和第二组各 24 个单词的分类列表。在编码、检索、两者或均不提供类别标签。当标签在编码或整个任务期间可用时,两组都表现出更好的回忆效果。ASD 个体对第二列表的回忆和聚类都减少了。在两组中,聚类和回忆呈正相关,且两组的主观组织水平也相似。这些发现与关于 ASD 中额叶和内侧颞叶对记忆贡献的理论有关。

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