Matsunami Katsuyoshi, Otsuka Hideaki, Kondo Kazunari, Shinzato Takakazu, Kawahata Masatoshi, Yamaguchi Kentaro, Takeda Yoshio
Department of Pharmacognosy, Graduate School of Biomedical Sciences, Hiroshima University, 1-2-3 Kasumi, Minami-ku, Hiroshima 734-8553, Japan.
Phytochemistry. 2009 Jul;70(10):1277-85. doi: 10.1016/j.phytochem.2009.07.020. Epub 2009 Aug 13.
A lignan glucoside, (+)-pinoresinol 4-O-[6''-O-galloyl]-beta-D-glucopyranoside (1), and two megastigmane glucosides, named macarangiosides E and F (2,3), together with 15 known compounds (4-18) were isolated from leaves of Macaranga tanarius (L.) Müll.-Arg. (Euphorbiaceae). Their structures were elucidated by spectroscopic and chemical analyses. In addition, the absolute stereochemistry of macarangiosides B and C isolated previously from the same plant was also determined for the first time. Compounds 1 and 2 were galloylated on glucose and possessed potent DPPH radical-scavenging activity.
从红背桂（大戟科土沉香属）的叶子中分离出一种木脂素糖苷，（+）-松脂醇4-O-[6''-O-没食子酰基]-β-D-吡喃葡萄糖苷（1），以及两种巨大戟烷糖苷，分别命名为红背桂苷E和F（2,3），同时还分离出15种已知化合物（4-18）。通过光谱和化学分析确定了它们的结构。此外，还首次确定了先前从同一植物中分离出的红背桂苷B和C的绝对立体化学结构。化合物1和2在葡萄糖上被没食子酰化，具有较强的清除DPPH自由基的活性。
