[紫花地丁化学成分的研究]
[Studies on chemical constituents from herbs of Viola yedoensis].
作者信息
Huang Jiqiu, Yang Jingzhi, Xue Qingchun, Yu Lei, Zhang Dongming
机构信息
Key Laboratory of Bioactive Substances and Resources Utilization of Chinese Herb Medicine Ministery of Education, Instituent of Materia Medica, Peking Union Medical College and Chinese Academy of Medical Sciences, Beijing 100050, China.
出版信息
Zhongguo Zhong Yao Za Zhi. 2009 May;34(9):1114-6.
OBJECTIVE
To study the chemical constituents of the whole plant of Viola yedoensis.
METHOD
The compounds were isolated by various chromatographic techniques and their structures were elucidated by their physicochemical properties and the analysis of their spectral data.
RESULT
Seven compounds were isolated and identified as esculetin (1), isoscopoletin (2), 6-hydroxymethyl-3-pyridinol (3),5,5-bi (6,7-dihydroxycoumarin) (4), 6,6,7,7-tetrahydroxy-5,8-bicoumarin (5), loliolide (6), dehydrololiolide (7).
CONCLUSION
Compounds 2-7 were isolated from V. yedoensis for the first time.
目的
研究紫花地丁全草的化学成分。
方法
采用多种色谱技术分离化合物，并通过其理化性质和光谱数据分析阐明其结构。
结果
分离并鉴定出7种化合物，分别为七叶内酯（1）、异七叶内酯（2）、6-羟甲基-3-吡啶醇（3）、5,5-联（6,7-二羟基香豆素）（4）、6,6,7,7-四羟基-5,8-双香豆素（5）、黑麦草内酯（6）、去氢黑麦草内酯（7）。
结论
化合物2 - 7首次从紫花地丁中分离得到。
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