Tierney Emily P, Kouba David J, Hanke C William
Laser and Skin Surgery Center of Indiana, Carmel, Indiana 46032, USA.
Dermatol Surg. 2009 Oct;35(10):1445-61. doi: 10.1111/j.1524-4725.2009.01258.x. Epub 2009 Jul 20.
Fractional photothermolysis (FP) is one of the most significant milestones in laser technology and resurfacing.
Review of the Medline English literature and recent international conferences regarding FP technology, applications, and indications.
Successful conditions treated with nonablative FP reported in the literature include acne scarring; dyschromia and fine wrinkling of photoaging on the face, chest, neck, and hands; melasma; poikiloderma of Civatte; nevus of Ota; scars; minocycline hyperpigmentation; telangiectatic matting; residual hemangioma; granuloma annulare; colloid milium; and disseminated superficial actinic porokeratosis. An advance in 2007 was the introduction of ablative FP (AFP), which results in significantly greater improvement in skin laxity and textural abnormalities. Most recently, AFP has demonstrated significantly greater improvement than nonablative FP in reducing acne scarring and skin redundancy and laxity associated with photoaging.
Through the induction of microthermal zones of injury, FP technology stimulates a robust and rapid wound healing response resulting in improvement in a diversity of aesthetic, inflammatory, and preneoplastic skin disorders. Further investigation into the technology and diverse array of cutaneous conditions that can benefit from FP is highly needed.
点阵激光是激光技术和皮肤磨削术最重要的里程碑之一。
回顾关于点阵激光技术、应用和适应症的Medline英文文献及近期国际会议。
文献报道非剥脱性点阵激光成功治疗的情况包括痤疮瘢痕；面部、胸部、颈部和手部光老化引起的色素沉着异常和细纹；黄褐斑；Civatte皮肤异色病；太田痣；瘢痕；米诺环素引起的色素沉着；毛细血管扩张性红斑；残余血管瘤；环状肉芽肿；胶样粟丘疹；以及播散性浅表性光化性汗孔角化症。2007年的一项进展是引入了剥脱性点阵激光（AFP），它在改善皮肤松弛和质地异常方面效果显著。最近，在减少痤疮瘢痕以及与光老化相关的皮肤多余和松弛方面，剥脱性点阵激光比非剥脱性点阵激光显示出更显著的改善。
通过诱导微小热损伤区，点阵激光技术激发强大而快速的伤口愈合反应，从而改善多种美学、炎症性和癌前皮肤疾病。非常需要进一步研究该技术以及可从点阵激光中受益的各种皮肤状况。
