Häuser W, Schmutzer G, Glaesmer H, Brähler E
Innere Medizin I, Klinikum Saarbrücken gGmbH, Winterberg 1, 66119 Saarbrücken.
Schmerz. 2009 Oct;23(5):461-70. doi: 10.1007/s00482-009-0817-2.
There are no data available from representative samples of the general German population on predictors of widespread pain (WP) and fibromyalgia syndrome (FMS).
A cross-sectional survey of a representative sample of the German general population with persons over 14 years old was conducted based on face-to-face contact using standardised questionnaires. The number of pain sites and the presence of WP and FMS were assessed by the regional pain scale (RPS), somatic symptom intensity was measured by the Patient Health Questionnaire (PHQ-15), depressed mood by PHQ 9 and health-related quality of life (HRQOL) by the Short Form Health Survey (SF-12).
Out of 4064 persons contacted, 2524 (62.1%) completed the study. The prevalence of CWP was 8.6% and of FMS 3.8%. The sex ratio for WP and FMS was 1:1. The variance of the number of pain sites was explained by older age, low social class index, high somatic symptom intensity, low depressed mood in 52.4% (p<0.001). Older age (OR 2.0, 95% CI 1.71; 2.36; <0.001), low social class index (OR 0.64; 95% CI 0.46; 0.91; p=0.01) and potential somatoform syndrome (OR 3.0; 95% CI 1.27; 7.15; p<0.001) predicted WP with a probability 94.4%. Older age (OR 1.39, 95% CI 1.19; 1.62, p <0.001), low social class index (OR 0.61, 95% CI .40, 0.93; p=0.02) and potential somatoform syndrome (OR 19.42; 95% CI 10.31; 36.61; p<0.001) predicted FMS with a probability 97.7%.
WP and FMS are components of a complex of high somatic symptom intensity, low social class index and older age.
目前尚无来自德国普通人群代表性样本的关于广泛疼痛（WP）和纤维肌痛综合征（FMS）预测因素的数据。
基于面对面接触，使用标准化问卷对德国14岁以上普通人群的代表性样本进行横断面调查。通过区域疼痛量表（RPS）评估疼痛部位数量以及WP和FMS的存在情况，通过患者健康问卷（PHQ - 15）测量躯体症状强度，通过PHQ 9测量抑郁情绪，通过简短健康调查（SF - 12）测量健康相关生活质量（HRQOL）。
在4064名被联系者中，2524人（62.1%）完成了研究。慢性广泛性疼痛（CWP）的患病率为8.6%，FMS的患病率为3.8%。WP和FMS的性别比为1:1。52.4%（p<0.001）的疼痛部位数量差异可由年龄较大、社会阶层指数较低、躯体症状强度较高、抑郁情绪较低来解释。年龄较大（比值比[OR] 2.0，95%置信区间[CI] 1.71；2.36；p<0.001）、社会阶层指数较低（OR 0.64；95% CI 0.46；0.91；p = 0.01）和潜在的躯体形式综合征（OR 3.0；95% CI 1.27；7.15；p<0.001）预测WP的概率为94.4%。年龄较大（OR 1.39，95% CI 1.19；1.62，p <0.001）、社会阶层指数较低（OR 0.61，95% CI 0.40，0.93；p = 0.02）和潜在的躯体形式综合征（OR 19.42；95% CI 10.31；36.61；p<0.001）预测FMS的概率为97.7%。
WP和FMS是高躯体症状强度、低社会阶层指数和年龄较大这一复合体的组成部分。
