Ropert A, Metral S
Service d'Explorations Fonctionnelles du Système Nerveux, Hôpital de Bicêtre, France.
Muscle Nerve. 1990 Feb;13(2):102-5. doi: 10.1002/mus.880130203.
Thirty-two patients with a mononeuropathy multiplex associated with a systemic necrotizing vasculitis were studied. The main abnormality was a loss of motor and sensory axons confirmed by electrophysiological and histological methods. A conduction block was observed in five patients, but only one was at a usual site of compression. Based on previous pathological studies and the experimental data in human and animals, the mechanism of the block is proposed to be ischemic. It is suggested that a conduction block in one nerve in a neuropathy with two or more individual nerves affected and with electrophysiological features of axonal degeneration may be due to a vasculitis.
对32例伴有系统性坏死性血管炎的多发性单神经病患者进行了研究。主要异常表现为运动和感觉轴突缺失，这已通过电生理和组织学方法得到证实。在5例患者中观察到传导阻滞，但只有1例发生在常见的受压部位。根据以往的病理学研究以及人和动物的实验数据，推测传导阻滞的机制为缺血性。有人提出，在累及两条或更多条神经且具有轴突变性电生理特征的神经病变中，某一条神经出现传导阻滞可能是由血管炎所致。
