韩国人群中三个常染色体STR基因座D21S1435、D21S1411和D21S1412的基因变异
Genetic variation of three autosomal STR loci D21S1435, D21S1411, and D21S1412 in Korean population.
作者信息
Lee Moon-Hee, Park So-Yeon, Kim Do-Jin, Kim Mi-Jin, Ryu Hyun-Mee, Cho Youl-Hee
机构信息
Laboratory of Medical Genetics, Cheil General Hospital and Women's Healthcare Center, Kwandong University College of Medicine, Seoul, Korea.
出版信息
Mol Biol Rep. 2010 Jan;37(1):99-104. doi: 10.1007/s11033-009-9679-z. Epub 2009 Aug 20.
The autosomal tetranucleotide short tandem repeat loci D21S1435, D21S1411 and D21S1412 were analyzed in samples of unrelated 200 Korean individuals. The loci showed no significant deviations from Hardy-Weinberg equilibrium. Alleles were assigned according to the International Society for Forensic Haemogenetics (ISFH) recommendations. The power of discrimination of the analyzed markers was found to be high for the populations, thereby facilitating the validation and efficiency of these STR markers in forensic human identification and paternity testing. To our knowledge, this is the first report of the nomenclature and the allele frequency data for these three STR loci in Korean population.
在200名无关韩国个体的样本中分析了常染色体四核苷酸短串联重复序列基因座D21S1435、D21S1411和D21S1412。这些基因座未显示出与哈迪-温伯格平衡有显著偏差。根据国际法医血液遗传学协会（ISFH）的建议对等位基因进行了分型。发现所分析标记对这些人群的鉴别力很高，从而有助于这些STR标记在法医个体识别和亲子鉴定中的验证及效率。据我们所知，这是韩国人群中这三个STR基因座的命名法和等位基因频率数据的首次报告。
Zotero 插件