Department of Orthopedic Surgery and Physical Rehabilitation, University of Massachusetts Medical School, Worcester, Massachusetts 01605-2982, USA.
J Arthroplasty. 2009 Sep;24(6 Suppl):9-14. doi: 10.1016/j.arth.2009.05.027.
This prospective, randomized protocol evaluated femoral head penetration after total hip arthroplasty in a young population. Forty-five patients randomly received either a cross-linked or conventional ultrahigh-molecular-weight polyethylene (UHMWPE) liner in a noncemented hemispheric cup (Trilogy, Zimmer, Warsaw, Ind) with a 28-mm femoral head. Radiostereometric analysis film pairs, Harris hip, UCLA, SF-12, and Western Ontario and McMaster Universities scores were obtained through 2 years. Median femoral head penetration was less among cross-linked compared to conventional liners as follows: 0.06 mm (0.04-0.08 mm) vs 0.08 mm (0.02-0.19 mm) at 6 months, 0.07 mm (-0.14 to 0.16 mm) vs 0.11 mm (0.01-0.27 mm) at 1 year, and 0.065 mm (-0.04 to 0.193 mm) vs 0.169 mm (0.09-0.22 mm) at 2 years. Clinical outcomes were similar between the groups. Highly cross-linked UHMWPE demonstrated 55% less femoral head penetration compared to conventional polyethylene at 2 years. Despite improvements in the manufacturing process and sterilization of conventional UHMWPE, the femoral head penetration rate is unchanged from historical standards.
本前瞻性、随机方案评估了年轻人群中全髋关节置换术后股骨头穿透情况。45 例患者随机接受了交联或传统超高分子量聚乙烯(UHMWPE)衬垫,使用非骨水泥半球形髋臼(Zimmer,印第安纳州华沙)和 28mm 股骨头。通过 2 年时间获得放射立体测量分析胶片对、Harris 髋关节评分、UCLA 评分、SF-12 评分、Western Ontario 和 McMaster 大学评分。交联组的股骨头穿透中位数明显小于传统衬垫组,结果如下:6 个月时为 0.06mm(0.04-0.08mm) vs 0.08mm(0.02-0.19mm);1 年时为 0.07mm(-0.14 至 0.16mm) vs 0.11mm(0.01-0.27mm);2 年时为 0.065mm(-0.04 至 0.193mm) vs 0.169mm(0.09-0.22mm)。两组的临床结果相似。与传统聚乙烯相比,高交联 UHMWPE 在 2 年内显示出 55%的股骨头穿透减少。尽管传统 UHMWPE 的制造工艺和灭菌得到了改进,但股骨头穿透率与历史标准相比没有变化。