Department of Chemistry, KAIST Institute for BioCentury & NanoCentury, 335 Science Road, Daejeon 305-701, Korea.
J Am Chem Soc. 2009 Sep 23;131(37):13224-5. doi: 10.1021/ja905183k.
A facile approach for material-independent surface modification using norepinephrine was investigated. pH-induced oxidative polymerization of norepinephrine forms adherent films on vastly different types of material surfaces of noble metals, metal oxides, semiconductors, ceramics, shape-memory alloys, and synthetic polymers. Secondary biochemical functionalizations such as immobilization of proteins and growth of biodegradable polyester on the poly(norepinephrine) films were demonstrated.
研究了一种使用去甲肾上腺素进行材料独立表面改性的简单方法。去甲肾上腺素的 pH 诱导氧化聚合在贵金属、金属氧化物、半导体、陶瓷、形状记忆合金和合成聚合物等各种不同类型的材料表面形成附着膜。在聚(去甲肾上腺素)膜上进行了二次生化功能化,如蛋白质固定和生物可降解聚酯的生长。