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Facile Conjugation of Biomolecules onto Surfaces via Mussel Adhesive Protein Inspired Coatings.通过受贻贝粘附蛋白启发的涂层将生物分子轻松共轭到表面。
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Mussel-inspired surface chemistry for multifunctional coatings.用于多功能涂层的贻贝启发式表面化学
Science. 2007 Oct 19;318(5849):426-30. doi: 10.1126/science.1147241.
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去甲肾上腺素:一种不依赖于材料的多功能表面修饰试剂。

Norepinephrine: material-independent, multifunctional surface modification reagent.

机构信息

Department of Chemistry, KAIST Institute for BioCentury & NanoCentury, 335 Science Road, Daejeon 305-701, Korea.

出版信息

J Am Chem Soc. 2009 Sep 23;131(37):13224-5. doi: 10.1021/ja905183k.

DOI:10.1021/ja905183k
PMID:19715340
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC2746854/
Abstract

A facile approach for material-independent surface modification using norepinephrine was investigated. pH-induced oxidative polymerization of norepinephrine forms adherent films on vastly different types of material surfaces of noble metals, metal oxides, semiconductors, ceramics, shape-memory alloys, and synthetic polymers. Secondary biochemical functionalizations such as immobilization of proteins and growth of biodegradable polyester on the poly(norepinephrine) films were demonstrated.

摘要

研究了一种使用去甲肾上腺素进行材料独立表面改性的简单方法。去甲肾上腺素的 pH 诱导氧化聚合在贵金属、金属氧化物、半导体、陶瓷、形状记忆合金和合成聚合物等各种不同类型的材料表面形成附着膜。在聚(去甲肾上腺素)膜上进行了二次生化功能化,如蛋白质固定和生物可降解聚酯的生长。