Wang Zhang, Min Sun-Joon, Danishefsky Samuel J
Department of Chemistry, Columbia University, Havemeyer Hall, 3000 Broadway, New York, New York 10027, USA.
J Am Chem Soc. 2009 Aug 12;131(31):10848-9. doi: 10.1021/ja9049433.
The neurotrophic diterpenoids, tricholomalides A and B, were synthesized in a concise fashion. Key transformations include a ketene [2 + 2] cycloaddition and a Grignard-type reaction. In the course of the synthesis, it was determined that the structures of tricholomalides A and B had originally been misassigned.
神经营养二萜类化合物，毛头鬼伞内酯A和B，以简洁的方式合成。关键转化包括烯酮[2 + 2]环加成反应和格氏型反应。在合成过程中，确定毛头鬼伞内酯A和B的结构最初被错误指定。
