Nimmich W, Zingler G, Falkenhagen U, Naumann G
Institut für Medizinische Mikrobiologie, Bereiches Medizin der Wilhelm-Pieck-Universität, Rostock, DDR.
Zentralbl Bakteriol. 1990 Apr;272(4):411-8.
The close connection between mannose-resistant hemagglutination (MRHA) and adhesion to uroepithelial cells of urinary E. coli with regard to the pathogenesis of urinary tract infection (UTI) prompted us to examine the hemagglutinating ability of 1499 E. coli strains from urine using human blood group OP1 erythrocytes. In 317 strains (21.2%), an MRHA was found. There were no significant differences in the prevalence of MRHA related to the isolation time and admitting hospital. A correlation was found between MRHA and the presence of P fimbriae in the strains investigated. Another association appears to exist between certain O:K:H serovars and distinct fimbrial antigens which had been serologically identified. The F11 antigen was detected most frequently and proved to be present in strains of serovars O1:K1:H-, O1::K1:H7, O2:K1:H-, O2:K1:H4, O2:K1:H7, and O15:K1:H7. The F8 antigen was strongly associated with serovar O18:K5:H-. O18:K5:H1 and O6:K5:H1 were apparently related to cross-reacting F14 antigens.
鉴于甘露糖抵抗性血凝反应（MRHA）与泌尿道大肠杆菌对尿道上皮细胞的黏附在尿路感染（UTI）发病机制中的密切联系，我们使用人O型红细胞来检测1499株尿液来源大肠杆菌的血凝能力。在317株菌株（21.2%）中发现了MRHA。MRHA的发生率与分离时间和收治医院无关。在所研究的菌株中，发现MRHA与P菌毛的存在相关。在某些经血清学鉴定的O:K:H血清型和不同菌毛抗原之间似乎也存在关联。F11抗原检测频率最高，且在血清型O1:K1:H-、O1::K1:H7、O2:K1:H-、O2:K1:H4、O2:K1:H7和O15:K1:H7的菌株中均有发现。F8抗原与血清型O18:K5:H-密切相关。O18:K5:H1和O6:K5:H1显然与交叉反应的F14抗原有关。
