Department of Physical Education and Sports Science, Democritus University of Thrace, Komotini, Greece.
Diabetes Care. 2009 Dec;32(12):2161-7. doi: 10.2337/dc08-1994. Epub 2009 Sep 3.
To evaluate the time course of leptin, adiponectin, and resting energy expenditure (REE) responses in overweight elderly males after acute resistance exercise protocols of various intensity configurations.
Forty inactive men (65-82 years) were randomly assigned to one of four groups (n = 10/group): control, low-intensity resistance exercise, moderate-intensity resistance exercise, and high-intensity resistance exercise. Exercise energy cost, REE, leptin, adiponectin, cortisol, insulin, lactate, glucose, nonesterified fatty acids (NEFAs), and glycerol were determined at baseline, immediately after exercise, and during a 72-h recovery period.
Exercise energy cost was lower in high-intensity than in low-intensity and moderate-intensity groups (221.6 +/- 8.8 vs. 295.6 +/- 10.7 and 281.6 +/- 9.8 kcal, P < 0.001). Lactate, glucose, NEFAs, and glycerol concentrations increased (P < 0.001) after exercise and returned to baseline thereafter in all groups. REE increased (P < 0.001) in all groups at 12 h in an intensity-dependent manner (P < 0.05). REE reached baseline after 48 h in the low- and moderate-intensity groups and after 72 h in the high-intensity group. Cortisol peaked in all active groups after exercise (P < 0.001) and remained elevated (P < 0.001) for 12 h. After adjustment for plasma volume shifts, leptin remained unaltered. Adiponectin concentration increased after 12 h and remained elevated for 24 h only in the high-intensity group (P < 0.001).
Resistance exercise does not alter circulating leptin concentration but does increase REE and adiponectin in an intensity-dependent manner for as long as 48 and 24 h, respectively, in overweight elderly individuals. It appears that resistance exercise may represent an effective approach for weight management and metabolic control in overweight elderly individuals.
评估不同强度组合的急性抗阻运动方案对超重老年男性瘦素、脂联素和静息能量消耗（REE）反应的时程。
40 名不活跃男性（65-82 岁）被随机分配到四个组之一（n = 10/组）：对照组、低强度抗阻运动组、中强度抗阻运动组和高强度抗阻运动组。在基线、运动后即刻和 72 小时恢复期内测定运动能量消耗、REE、瘦素、脂联素、皮质醇、胰岛素、乳酸、血糖、非酯化脂肪酸（NEFAs）和甘油。
高强度组的运动能量消耗低于低强度和中强度组（221.6 ± 8.8 比 295.6 ± 10.7 和 281.6 ± 9.8 kcal，P < 0.001）。运动后所有组的乳酸、血糖、NEFAs 和甘油浓度均升高（P < 0.001），此后均恢复至基线。所有组在 12 小时时REE 呈强度依赖性增加（P < 0.05）。低强度和中强度组在 48 小时后，高强度组在 72 小时后 REE 恢复至基线。所有运动组在运动后皮质醇峰值（P < 0.001），并在 12 小时内保持升高（P < 0.001）。校正血浆容量变化后，瘦素保持不变。脂联素浓度在 12 小时后增加，仅在高强度组持续升高 24 小时（P < 0.001）。
抗阻运动不会改变循环瘦素浓度，但会以强度依赖的方式分别增加 REE 和脂联素长达 48 小时和 24 小时，在超重老年人中。似乎抗阻运动可能是超重老年人体重管理和代谢控制的有效方法。
