Dunya Göz Hastanesi (World Eye Hospital), Istanbul, Turkey.
Ophthalmologica. 2010;224(2):122-5. doi: 10.1159/000235926. Epub 2009 Sep 2.
To evaluate the efficacy and complications of heavy silicone oil (Densiron 68) in primary inferiorly located retinal detachment.
Sixty-seven eyes of patients aged 24-79 years with inferior primary rhegmatogenous retinal detachment with/without proliferative vitreoretinopathy grades C and lower were included in the study. The mean duration of the Densiron endotamponade was 87 days (range, 60-180 days), with a mean follow-up after removal of 110 +/- 41 days.
Anatomical success was achieved in 64 of 67 eyes with completed follow-up. The mean visual acuity was changed significantly (p < 0.05). Partial superior redetachment occurred in 3 cases during endotamponade. No redetachment occurred after removal of the silicone oil. Postoperative best corrected visual acuity was better than 20/40 in 43 of cases at the end of follow-up. The mean intraocular pressure was 19.2 mm Hg during endotamponade follow-up. Mild to moderate intraocular inflammation was detected in 7 eyes. In 6 cases, adherence of residual bubble or bubbles was present after removal of the heavy silicone oil. Other complications, like elevated intraocular pressure (n = 6), emulsification (n = 8), temporary lens opacities (n = 14) or early cataract (n = 9), were detected after the operation.
Long-term endotamponade with Densiron in inferior retinal detachment appears to be a safe and useful option.
评估重硅油（Densiron 68）在原发性下方视网膜脱离中的疗效和并发症。
本研究纳入了 67 例年龄在 24-79 岁之间的患者，这些患者患有下方原发性孔源性视网膜脱离，伴或不伴有增殖性玻璃体视网膜病变 C 级及以下病变。Densiron 眼内填充的平均时间为 87 天（范围为 60-180 天），去除填充物后的平均随访时间为 110±41 天。
在完成随访的 67 只眼中，有 64 只眼达到了解剖学上的成功。平均视力明显改善（p<0.05）。在填塞期间，3 例发生部分上方再脱离。硅油去除后无再脱离。在随访结束时，43 例病例的最佳矫正视力优于 20/40。在填塞随访期间，平均眼压为 19.2mmHg。7 只眼出现轻度至中度眼内炎症。在 6 例中，去除重硅油后仍存在残余气泡或气泡的附着。其他并发症，如眼压升高（n=6）、乳化（n=8）、暂时晶状体混浊（n=14）或早期白内障（n=9），在手术后被发现。
在下方视网膜脱离中进行长期的 Densiron 眼内填塞似乎是一种安全有效的选择。
