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从龙葵中分离得到的两种新桉叶烷型倍半萜类化合物。

Two new eudesmane-type sesquiterpenoids from Olanum lyratum.

作者信息

Dai Sheng-Jun, Shen Li, Ren Yan

机构信息

School of Pharmaceutical Science, Yantai University, People's Republic of China.

出版信息

Nat Prod Res. 2009;23(13):1196-200. doi: 10.1080/14786410802396087.

Abstract

Two new eudesmane-type sesquiterpenoids, lyratol A-B (1 and 2), were isolated from the whole plant of Olanum lyratum Thunb and their structures were elucidated by extensive spectroscopic analyses. In addition, two new compounds were found to show significant cytotoxicity against selected cancer cells in vitro, including P-388 and HT-29.

摘要

从白英全草中分离得到两个新的桉叶烷型倍半萜类化合物,即lyratol A - B(1和2),并通过广泛的光谱分析确定了它们的结构。此外,发现这两个新化合物对包括P - 388和HT - 29在内的某些癌细胞具有显著的体外细胞毒性。

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