Centre for STD Research and Diagnostics, Bialystok, Poland.
Adv Med Sci. 2009;54(1):82-5. doi: 10.2478/v10039-009-0007-6.
The study objective was to evaluate the prevalence of urogenital Chlamydia trachomatis (C.tr.) infection in women with diagnosed infertility.
The study involved patients from the Department of Gynecological Endocrinology and from the Center for Reproductive Medicine "Kriobank" in Bialystok. Female patients (n=71), aged 23-41, were divided into two groups according to the main diagnosis: A--tubal infertility (23) and B--infertility of another origin (48). For direct testing, PCR method was used to detect C.tr. infection in cervical samples (Roche, Molecular Systems, N.J., USA). Specific IgA and IgG anti-chlamydial antibodies in the serum were determined by immunoenzymatic assay (medac, Hamburg, Germany). Diagnostic procedures were performed at the Centre for STD Research and Diagnostics in Bialystok.
In group A, C.tr. infection was detected in: 8.7% patients, in group B--8.3%. Specific anti-C.tr. antibodies IgA were detected in: 13.0% in group A and 6.3% in group B, IgG respectively in 39.1% and in 10.4%.
本研究旨在评估诊断为不孕的女性生殖道沙眼衣原体（C.tr.）感染的流行率。
该研究纳入了比亚韦斯托克妇科内分泌科和生殖医学中心“Kriobank”的患者。根据主要诊断，将 71 名年龄在 23-41 岁的女性患者分为两组：A 组为输卵管性不孕（23 例），B 组为其他原因不孕（48 例）。采用 PCR 法直接检测宫颈样本中的 C.tr.感染（罗氏，分子系统，新泽西州，美国）。采用免疫酶法（medac，汉堡，德国）检测血清中特异性 IgA 和 IgG 抗衣原体抗体。诊断程序在比亚韦斯托克性传播疾病研究和诊断中心进行。
在 A 组中，检测到 C.tr.感染的患者比例为 8.7%，在 B 组中为 8.3%。在 A 组中检测到特异性抗 C.tr.抗体 IgA 的患者比例为 13.0%，在 B 组中为 6.3%，IgG 分别为 39.1%和 10.4%。
