Diabetes and Metabolic Disease Research Centre, Hidaka Hospital, Gunma, Japan.
Endocr J. 2009;56(9):1079-82. doi: 10.1507/endocrj.k09e-197. Epub 2009 Sep 5.
We performed a receiver operator characteristic (ROC) curve analysis of 3915 men and 2032 women. Subjects who were diagnosed with two or more factors among high blood pressure, hyperglycaemia or high triglyceride and/or low HDL were classified as the metabolic syndrome group. By performing a ROC curve analysis, we have determined the cut-off point of waist circumference (WC) and BMI to define metabolic syndrome and further calculated the sensitivity and specificity of these two factors for the diagnosis. Cut-off point for the diagnosis of metabolic syndrome was 85 cm (men) and 80 cm (women) in WC and 24 (men) and 23 (women) in BMI. By combining these two factors, the sensitivity for the diagnosis increased to more than 80%. We conclude that it is beneficial to combine both WC and BMI for diagnosis of metabolic syndrome.
我们对 3915 名男性和 2032 名女性进行了受试者工作特征（ROC）曲线分析。将患有高血压、高血糖或高三酰甘油和/或低高密度脂蛋白血症两种及以上因素的受试者归类为代谢综合征组。通过 ROC 曲线分析，我们确定了腰围（WC）和 BMI 的截断值，以定义代谢综合征，并进一步计算了这两个因素对诊断的敏感性和特异性。代谢综合征的诊断截断值为 WC 男性 85cm，女性 80cm；BMI 男性 24，女性 23。通过结合这两个因素，诊断的敏感性提高到 80%以上。我们得出结论，联合 WC 和 BMI 对代谢综合征的诊断有益。
