Shanghai Innovation Center of TCM Health Service, Shanghai University of Traditional Chinese Medicine, No. 1200 Cailun Road, Shanghai, 201203, China.
Zhangjiang Community Health Service Center of Pudong New District, No. 458 Yijiang Road, Shanghai, 201210, China.
Sci Rep. 2018 Jan 10;8(1):385. doi: 10.1038/s41598-017-18854-1.
The purpose of this study was to compare the predictive ability of five obesity indices, including body mass index (BMI), waist circumference (WC), waist-to-height ratio (WHtR), waist-to-hip ratio (WHpR) and body adiposity index (BAI), to predict multiple non-adipose metabolic risk factors, including elevated blood pressure (BP), elevated fasting plasma glucose (FPG), elevated triglyceride (TG), reduced high-density lipoprotein cholesterol (HDL-C), elevated serum uric acid (SUA) and non-alcoholic fatty liver disease (NAFLD), in an elderly Chinese population. A total of 5685 elderly Chinese subjects (≥60 years) were recruited into our community-based cross-sectional study. Receiver operating characteristic curve (ROC) analyses were used to compare the predictive ability as well as determine the optimal cut-off values of the obesity indices for multiple metabolic risk factors. According to the areas under the receiver operating characteristic curve (AUC), BMI, WC and WHtR were able to similarly predict high metabolic risk in males (0.698 vs. 0.691 vs. 0.688), while in females, BMI and WC were able to similarly predict high metabolic risk (0.676 vs. 0.669). The optimal cut-off values of BMI, WC and WHtR in males were, respectively, 24.12 kg/m, 83.5 cm and 0.51, while in females, the values were 23.53 kg/m and 77.5 cm.
本研究旨在比较五种肥胖指数(包括体重指数 [BMI]、腰围 [WC]、腰高比 [WHtR]、腰臀比 [WHpR] 和身体脂肪指数 [BAI])预测多种非脂肪代谢危险因素的能力,这些危险因素包括血压升高、空腹血糖升高、甘油三酯升高、高密度脂蛋白胆固醇降低、血尿酸升高和非酒精性脂肪肝疾病(NAFLD)。共纳入 5685 名中国老年人(≥60 岁)进行基于社区的横断面研究。受试者工作特征曲线(ROC)分析用于比较肥胖指数预测多种代谢危险因素的能力,并确定其最佳截断值。根据 ROC 曲线下面积(AUC),BMI、WC 和 WHtR 可在男性中相似地预测高代谢风险(0.698 对 0.691 对 0.688),而在女性中,BMI 和 WC 可相似地预测高代谢风险(0.676 对 0.669)。男性中 BMI、WC 和 WHtR 的最佳截断值分别为 24.12 kg/m、83.5 cm 和 0.51,而女性的最佳截断值分别为 23.53 kg/m 和 77.5 cm。