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先天性风疹感染:单绒毛膜双羊膜囊单胎盘的单卵双胎之一感染风疹病毒。

Congenital rubella infection: escape of one monozygotic twin with two amnions, one chorion, and single placenta.

作者信息

Wang L N, Wang Y F, Horne C C, Shiao L C

机构信息

Department of Pediatrics, Taipei Municipal Jen-Ai Hospital, Taiwan, R.O.C.

出版信息

J Formos Med Assoc. 1990 Jan;89(1):30-3.

PMID:1973707
Abstract

We report a 2 amnions, 1 chorion, single placenta, monozygotic identical twins, who were born by a mother with a subclinical rubella infection during the gestation; one twin had a congenital rubella infection, the other escaped from it. Both twins were premature and small for their gestational age at birth. They both had an intraventricular hemorrhage ascribed to prematurity. One had a strong positive rubella IgM antibody for more than 3 months and a persistent IgG antibody for more than 1 year. The other had a fading rubella IgG antibody within 3 months, and a negative IgM. The baby with the congenital infection of rubella did not have a defective appearance, but the auditory brain stem evoked potential test showed abnormal findings. In monozygotic identical twins, vessel communication usually exist and the escape of a twin from rubella is a rare condition; there have been only two such events reported in the English literature.

摘要

我们报告了一例双羊膜、单绒毛膜、单胎盘的单卵同卵双胞胎,其母亲在孕期患有亚临床风疹感染;其中一个双胞胎患有先天性风疹感染,另一个未感染。两个双胞胎均早产且出生时小于孕周。他们都因早产发生了脑室内出血。其中一个风疹IgM抗体强阳性超过3个月,IgG抗体持续阳性超过1年。另一个风疹IgG抗体在3个月内逐渐消失,IgM为阴性。患有先天性风疹感染的婴儿外观无缺陷,但听觉脑干诱发电位测试显示异常结果。在单卵同卵双胞胎中,血管通常相通,一个双胞胎未感染风疹是一种罕见情况;英文文献中仅报道过两例此类事件。

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