节前神经的电刺激可增加交感神经节中酪氨酸羟化酶的活性。
Electrical stimulation of preganglionic nerve increases tyrosine hydroxylase activity in sympathetic ganglia.
作者信息
Zigmond R E, Ben-Ari Y
出版信息
Proc Natl Acad Sci U S A. 1977 Jul;74(7):3078-80. doi: 10.1073/pnas.74.7.3078.
Abstract
The effect of synaptic stimulation on tyrosine hydroxylase [tyrosine 3-monooxygenase: L-tyrosine, tetrahydropteridine:oxygen oxidoreductase (3-hydroxylating), EC 1.14.16.2] activity in the rat superior cervical ganglion was studied. The preganglionic cervical sympathetic trunk was stimulated unilaterally at 10 Hz for 30 min. Forty-eight hours later tyrosine hydroxylase activity was 33% higher on the stimulated than on the control side. The enzyme activity restimulated than on the control side. The enzyme activity remained elevated in the stimulated ganglia for 2 days. No change was observed in total ganglion protein. Comparable increases in tyrosine hydroxylase activity were observed in anesthetized and conscious animals.
摘要
研究了突触刺激对大鼠颈上神经节中酪氨酸羟化酶[酪氨酸3-单加氧酶：L-酪氨酸，四氢蝶呤：氧氧化还原酶（3-羟化），EC 1.14.16.2]活性的影响。节前颈交感干以10Hz单侧刺激30分钟。48小时后，受刺激侧的酪氨酸羟化酶活性比对照侧高33%。该酶活性在受刺激侧比对照侧再次刺激时更高。在受刺激的神经节中，酶活性持续升高2天。神经节总蛋白未观察到变化。在麻醉和清醒动物中均观察到酪氨酸羟化酶活性有类似增加。
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Proc Natl Acad Sci U S A. 1977 Jul;74(7):3078-80. doi: 10.1073/pnas.74.7.3078.
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本文引用的文献
1
Protein measurement with the Folin phenol reagent.使用福林酚试剂进行蛋白质测定。
J Biol Chem. 1951 Nov;193(1):265-75.
2
Preganglionic sympathetic activity in normal and in reserpine-treated cats.正常猫和利血平处理猫的节前交感神经活动
J Physiol. 1960 Jan;150(1):114-33. doi: 10.1113/jphysiol.1960.sp006377.
3
Increase in tyrosine hydroxylase activity after reserpine administration.利血平给药后酪氨酸羟化酶活性增加。
J Pharmacol Exp Ther. 1969 Sep;169(1):74-9.
4
Effect of nerve growth factor and its antiserum on tyrosine hydroxylase activity in mouse superior cervical sympathetic ganglion.神经生长因子及其抗血清对小鼠颈上神经节酪氨酸羟化酶活性的影响。
Brain Res. 1971 Jun 4;29(1):159-62. doi: 10.1016/0006-8993(71)90429-x.
5
Acceleration of noradrenaline biosynthesis by nerve stimulation.神经刺激对去甲肾上腺素生物合成的加速作用。
Life Sci. 1966 Jun;5(12):1071-5. doi: 10.1016/0024-3205(66)90089-0.
6
Inhiition of neuronally induced tyrosine hydroxylase by nitinic receptor blockade.通过烟碱样受体阻断抑制神经元诱导的酪氨酸羟化酶
Eur J Pharmacol. 1970 Apr;10(1):51-6. doi: 10.1016/0014-2999(70)90156-1.
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8
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