Chulabhorn Research Institute, Vibhavadi-Rangsit Highway, Bangkok, Thailand.
Planta Med. 2010 Feb;76(3):276-7. doi: 10.1055/s-0029-1186081. Epub 2009 Sep 9.
The biflavonoid, 3'',4',4''',5,5'',7,7''-heptahydroxy-3,8-biflavanone, known as GB1 (1), was isolated as a major constituent from Garcinia kola stem bark. GB1 (1) exhibited alpha-glucosidase and aromatase inhibitory activities, as well as antiplasmodial activity, but was not toxic against cell lines tested. GB1 (1) may be a potential dietary supplement or phytomedicine for the prevention of breast cancer and type 2 diabetes mellitus.
双黄酮类化合物 3'',4',4''',5,5'',7,7''-七羟基-3,8-双黄烷酮，称为 GB1（1），是从可乐果茎皮中分离出来的主要成分之一。GB1（1）表现出α-葡萄糖苷酶和芳香酶抑制活性以及抗疟原虫活性，但对测试的细胞系没有毒性。GB1（1）可能是预防乳腺癌和 2 型糖尿病的潜在膳食补充剂或植物药。
