Iglesias Alvaro, Muñiz Kilian
Institut de Chimie, UMR 7177, University of Strasbourg, 4 rue Blaise Pascal, F-67000 Strasbourg Cedex, France.
Chemistry. 2009 Oct 12;15(40):10563-9. doi: 10.1002/chem.200901199.
A complimentary diamination of alkenes by using homogeneous gold catalysts is described. The reaction is one of very few examples of homogeneous gold oxidation catalysis and proceeds with high selectivity under mild conditions. Individual steps of the suggested catalytic cycle were investigated on isolated model gold complexes, and new pathways for gold-catalyzed amination reactions were established. The key step is an intramolecular alkyl-nitrogen bond formation from a gold(III) intermediate. This process validates the concept of reductive elimination from high oxidation catalyst states for this type of C-N bond forming reactions.
描述了一种使用均相金催化剂对烯烃进行互补双胺化反应。该反应是均相金氧化催化中极少数的例子之一，在温和条件下具有高选择性。在分离的模型金配合物上研究了所提出催化循环的各个步骤，并建立了金催化胺化反应的新途径。关键步骤是由金（III）中间体形成分子内烷基 - 氮键。这一过程验证了对于此类C - N键形成反应，从高氧化态催化剂进行还原消除的概念。
