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用于治疗慢性伤口的局部抗菌剂。

Topical antimicrobial agents for the treatment of chronic wounds.

作者信息

Ousey Karen, McIntosh Caroline

机构信息

University of Huddersfield, Yorkshire.

出版信息

Br J Community Nurs. 2009 Sep;14(9):S6, S8, S10 passim. doi: 10.12968/bjcn.2009.14.Sup4.43909.

DOI:10.12968/bjcn.2009.14.Sup4.43909
PMID:19749669
Abstract

Chronic wounds are commonly observed in acute and community settings. The management of chronic wounds represents a significant proportion of health-care resources and makes up a substantial amount of contact time with community-based nurses spending approximately 25% to 50% of their time treating wounds. Chronic wounds often exhibit increased bacterial burden that can negatively impact upon patients, reduce their quality of life and substantially increase treatment costs for health care providers. Antibiotic resistance has become a major medical and public health problem, and interest has been generated in the use of topical therapies to manage wound infection. This article presents an overview of the historical use of honey, silver and iodine for the treatment of infected wounds progressing through to modern day use and the current evidence base for the use of these antimicrobial agents in the management of infected wounds.

摘要

慢性伤口在急性和社区环境中较为常见。慢性伤口的管理占用了相当比例的医疗保健资源,并且在社区护士的接触时间中占了很大一部分,她们大约花费25%至50%的时间来处理伤口。慢性伤口通常表现出细菌负荷增加,这会对患者产生负面影响,降低他们的生活质量,并大幅增加医疗服务提供者的治疗成本。抗生素耐药性已成为一个主要的医学和公共卫生问题,人们对使用局部疗法来处理伤口感染产生了兴趣。本文概述了蜂蜜、银和碘在治疗感染伤口方面的历史应用,直至现代的使用情况,以及这些抗菌剂在处理感染伤口方面的当前证据基础。

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Br J Community Nurs. 2009 Sep;14(9):S6, S8, S10 passim. doi: 10.12968/bjcn.2009.14.Sup4.43909.
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Asian Pac J Trop Biomed. 2011 Oct;1(5):370-5. doi: 10.1016/S2221-1691(11)60082-8.
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