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多中心前瞻性观察研究:医用蜂蜜(美皮康)在专业伤口护理中的应用。

Multicentre prospective observational study on professional wound care using honey (Medihoney™).

机构信息

Department of Paraplegia and Technical Orthopaedics, Insurance Association Trauma Centre, 67071 Ludwigshafen, Germany.

出版信息

Int Wound J. 2013 Jun;10(3):252-9. doi: 10.1111/j.1742-481X.2012.00970.x. Epub 2012 Apr 11.

Abstract

In recent years, the treatment of wounds with honey has received an increasing amount of attention from healthcare professionals in Germany and Austria. We conducted a prospective observational multicentre study using Medihoney™ dressings in 10 hospitals - nine in Germany and one in Austria. Wound-associated parameters were monitored systematically at least three times in all patients. Data derived from the treatment of 121 wounds of various aetiologies over a period of 2 years were analysed. Almost half of the patients were younger than 18 years old, and 32% of the study population was oncology patients. Overall, wound size decreased significantly during the study period and many wounds healed after relatively short time periods. Similarly, perceived pain levels decreased significantly, and the wounds showed noticeably less slough/necrosis. In general, our findings show honey to be an effective and feasible treatment option for professional wound care. In addition, our study showed a relationship between pain and slough/necrosis at the time of recruitment and during wound healing. Future comparative trials are still needed to evaluate the extent to which the positive observations made in this and other studies can definitely be attributed to the effects of honey in wound care.

摘要

近年来,德国和奥地利的医疗保健专业人员越来越关注使用蜂蜜治疗伤口。我们在 10 家医院(德国 9 家,奥地利 1 家)进行了一项前瞻性观察性多中心研究,使用 Medihoney™敷料对所有患者至少进行了 3 次系统监测。分析了为期 2 年治疗的 121 种不同病因的伤口数据。将近一半的患者年龄小于 18 岁,32%的研究人群为肿瘤患者。总的来说,研究期间伤口大小明显缩小,许多伤口在较短的时间内愈合。同样,疼痛程度明显降低,伤口的腐肉/坏死明显减少。总体而言,我们的研究结果表明蜂蜜是一种有效且可行的专业伤口护理治疗选择。此外,我们的研究还表明,招募时和伤口愈合过程中的疼痛与腐肉/坏死之间存在关联。仍需要进行未来的对照试验,以评估在本研究和其他研究中观察到的积极结果在多大程度上可以归因于蜂蜜在伤口护理中的作用。

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